Results 121 to 130 of about 3,724,225 (314)

Evaluating the tangible and intangible parameters of cultural heritage: an economic meta-analysis in a global context

Discover Sustainability
Sustainable development ensures the longevity of civilization by balancing economic growth, environmental protection, and social equity. The present study evaluates cultural heritage assets via a meta-regression analysis function transfer, in which 85 ...
George E. Halkos, Phoebe C. Koundouri, Panagiotis-Stavros C. Aslanidis, Angelos Plataniotis   +3 more
doaj   +1 more source

Evaluation of gestation length and birth weight of offspring of Polish native cattle breeds in context of estimating genetic parameters [PDF]

, 2018
A. Nienartowicz–Zdrojewska, Z. Sobek, Jolanta Różańska-Zawieja   +2 more
openalex   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Analysis of water quality parameters in foothill rivers in the context of the construction of dam reservoirs

Frontiers in Environmental Science
Backwater in retention reservoirs is potentially exposed to various contaminants, such as nutrients or heavy metals. Therefore, actions performed at the construction planning stage for such a facility are crucial; they are aimed at precisely evaluating ...
Maksymilian Połomski, Maksymilian Połomski, Mirosław Wiatkowski, Paweł Tomczyk   +3 more
doaj   +1 more source

The Statistical Analysis of Pharmacokinetic Parameters in the Context of Bioequivalence Testing of Two Anthelmintic Formulas Based on Ivermectine and Triclabendazole in Sheep [PDF]

, 2019
Lénárd Farczádi, Laurian Vlase, Orsolya Melles, Ramona Tolomeiu, Octavia Tamas-Krumpe, Andreea Buta, Laurențiu Ognean   +6 more
openalex   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Analysis of the Matching Media Effects by Microwave Field Distribution Simulations for the Cylindrically Layered Human Arm Model

Applied Sciences
In this study, a method is presented to determine the matching media parameters that maximize the electromagnetic energy penetrating into the human arm modeled as a radially stratified cylinder.
Tanju Yelkenci
doaj   +1 more source