Results 51 to 60 of about 1,142,494 (337)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Individual, collective and contextual dimensions of sustainable lifestyle change in daily life contexts: an integrated perspective

open access: yesFrontiers in Psychology
This paper aims to develop a conceptual and theoretical perspective on sustainable lifestyle change according to a multidisciplinary approach. In particular, we discuss the interplay between three orders of factors that, according to the literature and ...
Eugenio De Gregorio   +5 more
doaj   +1 more source

Management Control Systems and Contextual Variables in the Hospitality Industry [PDF]

open access: yes, 2013
Purpose – The paper examined management control systems (MCS) in Indonesian hospitality sector. This study examines the impact of six contextual factors at one time to determine the importance of each factor on the design of MCS.
Fauzi , Hasan   +2 more
core  

Understanding confounding effects in linguistic coordination: an information-theoretic approach

open access: yes, 2015
We suggest an information-theoretic approach for measuring stylistic coordination in dialogues. The proposed measure has a simple predictive interpretation and can account for various confounding factors through proper conditioning.
Galstyan, Aram   +2 more
core   +3 more sources

Changing times in England: the influence on geography teachers’ professional practice [PDF]

open access: yes, 2012
School geography in England has been characterised as a pendulum swinging between policies that emphasise curriculum and pedagogy alternately. In this paper, I illustrate the influence of these shifts on geography teacher's professional practice, by ...
Alexander R.   +47 more
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Developing a Conceptual Framework of Contextual Factors Affecting Knowledge Transfer in Transnational Projects [PDF]

open access: yesمدیریت صنعتی, 2019
Objective:Nowadays, with significant growth in the number of organizations, they seek to increase their competitive advantages as much as possible. One of the effective approaches is knowledge management, through which organizations try to re-exploit the
Fariba Shoeleh   +3 more
doaj   +1 more source

Mathematical Explanation: A Contextual Approach [PDF]

open access: yes, 2017
PurposeIn this article, we aim to present and defend a contextual approach to mathematical explanation.MethodTo do this, we introduce an epistemic reading of mathematical explanation.ResultsThe epistemic reading not only clarifies the link between ...
Delarivière, Sven   +2 more
core  

Looking for a psychology for the inner rational agent [PDF]

open access: yes, 2015
Research in psychology and behavioural economics shows that individuals’ choices often depend on ‘irrelevant’ contextual factors. This presents problems for normative economics, which has traditionally used preference-satisfaction as its criterion.
Sugden, Robert
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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