Results 111 to 120 of about 253,119 (310)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Automated vicarious radiometric validation of spaceborne thermal infrared sensors at non-dedicated validation sites using deep learning-based cloud filtering

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
Vicarious calibration/validation (Cal/Val) is essential for ensuring the radiometric accuracy of spaceborne thermal infrared (TIR) sensors. Anticipating an increase in the number of TIR sensors in the near future, this study developed an automated ...
Soushi Kato, Toru Kouyama
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Style Transfer-Based Augmentation for Side-Scan Sonar Images

open access: yes水下无人系统学报
Side-scan sonar(SSS) has been extensively adopted in ocean exploration because of its stability and efficiency when deployed on autonomous undersea vehicles(AUVs).
Zhongyu BAI   +3 more
doaj   +1 more source

Efficient paddy field mapping using Landsat-8 imagery and object-based image analysis based on advanced fractel net evolution approach

open access: yesGIScience & Remote Sensing, 2017
This paper proposes an efficient paddy field mapping method using object-based image analysis and a bitemporal data set acquired by Landsat-8 Operational Land Imager.
Tengfei Su
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Masked Channel Modeling Enables Vision Transformers to Learn Better Semantics

open access: yesEntropy
Leveraging the ability of Vision Transformers (ViTs) to model contextual information across spatial patches, Masked Image Modeling (MIM) has emerged as a successful pre-training paradigm for visual representation learning by masking parts of the input ...
Jiayi Chen   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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