Results 81 to 90 of about 45,354 (260)

Exploring the Interplay between Biblical Culture and African Traditional Customs: A Contextual Investigation [PDF]

Pharos Journal of Theology
This study examines the relationship between biblical culture (Old Testament) and African traditional customs to identify similarities, differences, and contextual integration in modern Christian expression.
Bello Oluwaniyi Samuel, Ayegboyin Abimbola Christianah, Lateju Olanrewaju Iyanuoluwa   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Detecting Chinese Disinformation with Fine–Tuned BERT and Contextual Techniques

Applied Artificial Intelligence
In the digital age, misinformation poses a significant threat to social cohesion, digital platform integrity, and political stability, particularly in countries with large online populations like China.
Lixin Yun, Sheng Yun, Haoran Xue
doaj   +1 more source

Missional Contextual Theology for Christian Ethics and Education in the Age of Disruption: A Framework for Scholars, Practitioners, and Faith-Based Educators [PDF]

Pharos Journal of Theology
The age of disruption—driven by digital transformation, rapid cultural shifts, and emerging ethical challenges—demands a renewed theological framework for Christian ethics and education.
Tonny Andrian Stefanus
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Structural Limits of Installation-Time Integrity Assurance: A Lifecycle-Based Accountability Framework for Over-the-Air-Enabled Physical AI Systems

IEEE Access
Installation-time integrity assurance is widely used as a foundational trust mechanism in over-the-air (OTA) software update ecosystems. By verifying cryptographic authenticity and artifact immutability at deployment, such mechanisms establish a provable
Ho Myung Kim, Eun Hwan Lee
doaj   +1 more source

Akademiese protokol in die teologiese wetenskap

HTS Teologiese Studies/Theological Studies, 1997
Academic protocol in theological science. Academic protocol in theological science determines the guidelines according to which the theologian applies theology as science. There is an inevitable interaction between the theological practice of science and 
L. J.L Steenkamp
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The Danger of Contextual Integrity

Business Ethics Quarterly
Contextual integrity has now become a (the?) dominant academic theory of privacy. It identifies privacy as both complex and social, two alluring attributes that other leading theories reject. Scholars who engage contextual integrity mostly do so only to convey their confidence in it as their working framework.
openaire   +1 more source