Results 151 to 160 of about 81,397 (309)

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

Correction: How do patients, medical assistants and physicians accept and experience tablet-based cognitive testing by medical assistants in general practice? - A qualitative study. [PDF]

BMC Prim Care
Rolke K, Rosendahl C, Weckbecker K, Hanke A, Wagner M, Nissen L, Reimer LM, Jonas S, Schaper P, Thyrian JR, Schweizer F, Tillmann J.   +11 more
europepmc   +1 more source

Business process contextualisation via context analysis [PDF]

, 2010
Ali, Raian, Dalpiaz, Fabiano, de la Vara, Jose Luis, Giorgini, Paolo, Sanchez, Juan   +4 more
core  

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Testing the case for contextualisation within the Framework for Excellence [PDF]

, 2008

core  

The ethics of suspicion in the study of religions

, 2007
In this essay I outline some beliefs and practices among lowland christianised peoples in the Philippines relating primarily to the existence of spirits which are believed to be responsible for causing illness, attending to their imbrication with ...
Tremlett, Paul-Francois
core  

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Towards causal validation and clinical translation of the PAK2-fibroblast axis in idiopathic pulmonary fibrosis. [PDF]

Eur Respir J
Sun M, Zang D, Chen J.
europepmc   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

Advanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee, Donghoon Moon, Ziyan Qian, Jinwoo Kim, Changheon Kim, Yeojin Lee, Hyobin Yoo, Richard B. Wilson, Qiye Zheng, Gwan‐Hyoung Lee, Hyejin Jang   +10 more
wiley   +1 more source

Contextualisation of the safeTALK™ Suicide Prevention Program: A Descriptive Qualitative Study. [PDF]

Health Expect
Poudel RP, Jefferies D, Pathrose SP, Gutierrez PM, Ramjan LM.   +4 more
europepmc   +1 more source