Results 41 to 50 of about 81,397 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Red Guide 46: The CEM Model contextualising in-sessional language and study skills support for international and EU students [PDF]
, 2008 This revised guide is designed to present the background, research and preliminary findings relating to a key area emerging in Higher Education institutions in the UK, that of providing academic language and study skills support to international students
Porter, Elizabeth, Sloan, Diane
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Verbum et EcclesiaThe article is a concise rendition of the author’s inaugural lecture and tracks his academic journey with the contextualisation of practical theology and pastoral care in an African context.
Alfred R. Brunsdon
doaj +1 more source
An information literacy integration model and its application in higher education [PDF]
, 2011 Purpose - The purpose of this paper is to present a model for curricular integration of information literacy for undergraduate programs in higher education.
Wang, Li
core +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Surfaces, depths and hypercubes: Meyerholdian scenography and the fourth dimension [PDF]
, 2015 An appreciation of Meyerhold’s engagement with theatrical space is fundamental to understanding his directorial and pedagogic practice. This article begins by establishing Meyerhold’s theoretical and practical engagement with theatre as a fundamentally ...
Apollinaire Guillaume +13 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Verbum et Ecclesia, 2020 Theology is never performed in a vacuum. One’s context impacts on theology and life. Local peculiarities have a huge impact on the needs and expectations of individuals and society at large. Ignoring the local context can have a detrimental impact on the
Jonathan M. Womack +2 more
doaj +1 more source
Évaluation de la contextualisation de tweets [PDF]
, 2013 National audienceCet article s'intéresse à l'évaluation de la contextualisation de tweets. La contextualisation est définie comme un résumé permettant de remettre en contexte un texte qui, de par sa taille, ne contient pas l'ensemble des éléments qui ...
Bellot, Patrice +4 more
core +3 more sources