Results 51 to 60 of about 149,870 (301)
Architectural interpretations of spatial form based on cellular automata with application in balneal contexts [PDF]
The concept of cellular automata (CA) has been challenging various disciplines for many decades. In this study the concept has been examined in the process of spatial form generation.
Petruševski Ljiljana +2 more
doaj
Strategic Design through Brand Contextualization [PDF]
Providing meaningful customer experience is at the core of any successful business activity. Brands can function as vehicles to bundle the ingredients of experience together and give them structure by which consumers are able to understand and interpret ...
Karjalainen, Toni-Matti +2 more
core
Ambivalent pasts: colonial history and the theatricalities of ethnographic display [PDF]
In the twenty-first century, museums holding ethnographic collections have come under scrutiny for their implication in colonial history, and many have started to address this problematic legacy, often in conscious attempts to move beyond the colonial as
Bachmann, Michael
core +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Constraint contextual rewriting
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
ARMANDO, ALESSANDRO, RANISE S.
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Contexts for studying a medieval city, or On the benefits of “fruitless” discussions in the history of historical science [PDF]
In the article, the author continues reflections on the fundamental importance and heuristic potential of the consistent study of materials of scientific discussions for historical-historiographic research.
Repina, Lorina P.
doaj +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source

