Results 131 to 140 of about 3,159 (255)

A university‐certified course on dossier assessment for regulatory scientists in Africa—Reporting on our 5‐year experience

British Journal of Clinical Pharmacology, EarlyView.
Aim The shortage of trained clinical assessors in African National Regulatory Authorities (NRAs) poses a challenge to effective regulatory decision‐making. Developed in line with the World Health Organization's (WHO) Global Competency Framework (WHO‐GCF), a university‐certified short course, Dossier assessment for clinical assessors in Africa, was ...
Stephanie Leigh, Boitumelo Semete‐Makokotlela, Ivana Škrnjug‐Yudov, David Mukanga, Delese Mimi Darko, Eric Karikari‐Boateng, Peter Stonier, Luther Gwaza, Precious Matsoso, Bernd Rosenkranz, Birka Lehmann, Arnold G. Vulto, John G. Woodland, Shabir Banoo, Frieda Shigwedha, Maphutheho Selikane, Unathi Mabona‐Mgoqi, Asare Yeboah, Ntombi Mthembu, Goonaseelan ( Colin) Pillai   +19 more
wiley   +1 more source

The Antarctic coastal ocean heat budget is dominated by heat loss to land ice melt. [PDF]

Sci Adv
Moorman R, Thompson AF, Youngs MK, Stewart AL.   +3 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source

Circulation and ocean-ice shelf interaction beneath the Denman and Shackleton Ice Shelves. [PDF]

Sci Adv
Rintoul SR, van Wijk EM, Herraiz-Borreguero L, Rosevear MG.   +3 more
europepmc   +1 more source

Acute effects of THC and a CBD+THC combination on cardiovascular haemodynamics and respiratory muscle activity during loaded breathing in healthy adults: A randomized placebo‐controlled crossover study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino, Marina Lyra L. C. Fagundes, Bruno Lobão Soares, Rodrigo Torres‐Castro, Matias Otto‐Yañez, Emerson Arcoverde Nunes, Matheus Freitas Fernandes Pedrosa, Jéssica Danielle Medeiros da Fonsêca, Vanessa R. Resqueti, Guilherme Augusto de Freitas Fregonezi   +9 more
wiley   +1 more source

Channelized topography amplifies melt-sensitivity of cold Antarctic ice shelves. [PDF]

Nat Commun
Zhou Q, Hattermann T, Zhao C, Gladstone R, Lauber J, Uotila P, Morris A.   +6 more
europepmc   +1 more source

Lessons from local area special educational needs and disability inspections: A content analysis of Ofsted and Care Quality Commission outcome letters

British Educational Research Journal, EarlyView.
Abstract The growing concern about demand for, and provision of, support for children and young people with special educational needs and disabilities (SEND) has led the English government to announce a review of the system, which many describe as being in crisis.
Ariadna Albajara Sáenz, Isaac Winterburn, Jacob Matthews, Anne‐Marie Burn, Tamsin Ford, Jennifer Saxton   +5 more
wiley   +1 more source

Tracking rehabilitated sea turtles in the Indian Ocean using satellite telemetry: Insights into behaviour, ecology, and conservation implications. [PDF]

PLoS One
Himpson K, Le Berre T, Hodges E.
europepmc   +1 more source

Understanding Plant Parasitism: Hydnora Africana and European Scientific Practice in the Early Nineteenth Century**

Berichte zur Wissenschaftsgeschichte, EarlyView.
This article will analyze the uncertainties around collecting and classifying Hydnora africana in the first half of the nineteenth century. Emerging from the distinctive dryland ecologies of South Africa, Hydnora was interpreted as strange and cryptic by Europeans primarily because it is a root parasite—a complex floral trait that was little understood.
Katherine Arnold
wiley   +1 more source