Results 41 to 50 of about 53,826 (301)

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Glacial-interglacial variability in ocean oxygen and phosphorus in a global biogeochemical model [PDF]

Biogeosciences, 2013
Increased transfer of particulate matter from continental shelves to the open ocean during glacials may have had a major impact on the biogeochemistry of the ocean. Here, we assess the response of the coupled oceanic cycles of oxygen, carbon, phosphorus,
V Palastanga, C. P. Slomp, C. Heinze
doaj   +1 more source

Hypsometry, Volume and Physiography of the Arctic Ocean and Their Paleoceanographic Implications [PDF]

, 2003
Recent analyses of the International Bathymetric Chart of the Arctic Ocean (IBCAO) grid model include: Hypsometry (the distribution of surface area at various depths); ocean volume distribution; and physiographic provinces [Jakobsson 2002; Jakobsson et ...
Grantz, Arthur, Jakobsson, Martin, Kristoffersen, Yngue, Macnab, Ron   +3 more
core   +1 more source

Influence of hydrodynamic processes on the fate of sedimentary organic matter on continental margins [PDF]

, 2018
Understanding the effects of hydrodynamic forcing on organic matter (OM) composition is important for assessment of organic carbon (OC) burial in marginal seas on regional and global scales.
Aller, Aller, Arnarson, Bao, Bao, Bauer, Bianchi, Bianchi, Bianchi, Blair, Blair, Blair, Bröder, Burdige, Burdige, Cameron McIntyre, Canuel, Cartapanis, Cathalot, Chen, Coppola, Cui, Daniel B. Montluçon, Drenzek, Eglinton, Galy, Gao, Goñi, Griffith, Guo, Harris, Hedges, Hilton, Hilton, Hwang, Inthorn, Kao, Keil, Keil, Kusch, Kusch, Leithold, Li, Lie, Liu, Liu, Liu, Liu, Luo, Marwick, Mayer, McCave, McCave, McCave, Meixun Zhao, Milliman, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Muller-Karger, Nuwer, Ohkouchi, Pawlowicz, Pedrosa-Pàmies, Qiao, Rui Bao, Saito, Shah, Stuiver, Su, Tao, Tao, Tesi, Tesi, Tesi, Tesi, Tessa S. van der Voort, Thomsen, Thomsen, Timothy I. Eglinton, Voort, Wagner, Wakeham, Wang, Wang, Wang, Wang, Wang, Wang, Wu, Xinyu Guo, Xu, Yang, Yang, Yang, Yang, Yao, Yao, Zhu, Zonneveld   +102 more
core   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov, Alexander F. Santillo, Patrick R. Hof   +2 more
wiley   +1 more source

Strong ice-ocean interaction beneath Shirase Glacier Tongue in East Antarctica

Nature Communications, 2020
East Antarctic ice shelves typically have cold ice cavities with low basal melt rates. Here the authors direct observational evidence of high basal melt rates beneath Shirase Glacier Tongue in East Antarctica, driven by inflowing warm water guided by a ...
Daisuke Hirano, Takeshi Tamura, Kazuya Kusahara, Kay I. Ohshima, Keith W. Nicholls, Shuki Ushio, Daisuke Simizu, Kazuya Ono, Masakazu Fujii, Yoshifumi Nogi, Shigeru Aoki   +10 more
doaj   +1 more source

Response of Pacific-sector Antarctic ice shelves to the El Niño/Southern Oscillation. [PDF]

, 2018
Satellite observations over the past two decades have revealed increasing loss of grounded ice in West Antarctica, associated with floating ice shelves that have been thinning.
Adusumilli, S, Fricker, HA, Howard, S, Padman, L, Paolo, FS, Siegfried, MR   +5 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Persistent warm-eddy transport to Antarctic ice shelves driven by enhanced summer westerlies

Nature Communications
The offshore ocean heat supplied to the Antarctic continental shelves by warm eddies has the potential to greatly impact the melting rates of ice shelves and subsequent global sea level rise. While featured in modeling and some observational studies, the
Libao Gao, Xiaojun Yuan, Wenju Cai, Guijun Guo, Weidong Yu, Jiuxin Shi, Fangli Qiao, Zexun Wei, Guy D. Williams   +8 more
doaj   +1 more source

The global marine phosphorus cycle: sensitivity to oceanic circulation [PDF]

Biogeosciences, 2007
A new mass balance model for the coupled marine cycles of phosphorus (P) and carbon (C) is used to examine the relationships between oceanic circulation, primary productivity, and sedimentary burial of reactive P and particulate organic C (POC), on ...
C. P. Slomp, P. Van Cappellen
doaj