Results 121 to 130 of about 129,344 (267)

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

open access: yesAdvanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu   +10 more
wiley   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu   +9 more
wiley   +1 more source

The degraded contingency test fails to detect habit induction in humans. [PDF]

open access: yesPLoS One
Molinero S   +6 more
europepmc   +1 more source

All‐In‐One Thermal Protection: Multifunctional Synergy in Hierarchically Structured Dual‐Oxide Nanofiber Aerogel

open access: yesAdvanced Science, EarlyView.
Through a cross‐scale structural design, a lightweight, heat‐resistant, and thermal‐insulating streamlined dual‐oxide nanofiber aerogel is prepared to achieve exceptional thermomechanical stability. Structural design of ceramic fibrous aerogel toward thermal protection, illustrating thermal insulation and stress dissipation.
Zijian Zhao   +9 more
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

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