Results 141 to 150 of about 757,037 (385)

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu   +23 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

open access: yesAdvanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao   +10 more
wiley   +1 more source

Divine Contingency [PDF]

open access: yes, 2014
Bohn, Einar Duenger
core   +1 more source

Enumerating contingency tables via random permanents

open access: yes, 2005
Given m positive integers R=(r_i), n positive integers C=(c_j) such that sum r_i = sum c_j =N, and mn non-negative weights W=(w_{ij}), we consider the total weight T=T(R, C; W) of non-negative integer matrices (contingency tables) D=(d_{ij}) with the row
Barvinok, Alexander
core   +3 more sources

A Self‐Organized Liquid Reaction Container for Cellular Memory

open access: yesAdvanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee   +4 more
wiley   +1 more source

Contingency-Constrained Unit Commitment With Intervening Time for System Adjustments

open access: yes, 2016
The N-1-1 contingency criterion considers the con- secutive loss of two components in a power system, with intervening time for system adjustments. In this paper, we consider the problem of optimizing generation unit commitment (UC) while ensuring N-1-1 ...
Chen, Richard Li-Yang   +3 more
core  

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Evaluation criteria for software classification inventories, accuracies, and maps [PDF]

open access: yes
Statistical criteria are presented for modifying the contingency table used to evaluate tabular classification results obtained from remote sensing and ground truth maps. This classification technique contains information on the spatial complexity of the
Jayroe, R. R., Jr.
core   +1 more source

Home - About - Disclaimer - Privacy