Results 151 to 160 of about 760,810 (388)

Reconstructing Chi-squared Intra-table Distances in the Analysis of a Set of Contingency Tables [PDF]

open access: yes
To study similarities among the set of rows -and columns- of a contingency table, Correspondence Analysis uses chi-squared distances between row profiles -and column profiles- of that table.
Goitisolo Lezama, Beatriz   +1 more
core  

A Self‐Organized Liquid Reaction Container for Cellular Memory

open access: yesAdvanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee   +4 more
wiley   +1 more source

Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD

open access: yesAdvanced Science, EarlyView.
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du   +6 more
wiley   +1 more source

WILDFLOWERS AND WONDER: A PASTOR'S WANDERINGS IN THE RELIGION‐SCIENCE WILDERNESS

open access: yesZygon, 1994
. In this paper, I explore, as a Christian and a parish pastor, what drew me into the religion‐science dialogue and what keeps me involved. Encounters with nature and readings of evolutionary theory answer some questions and raise others, especially ...
doaj   +2 more sources

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

open access: yesAdvanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong   +13 more
wiley   +1 more source

ROBERT J. RUSSELL'S ESCHATOLOGICAL THEOLOGY IN THE CONTEXT OF COSMOLOGY

open access: yesZygon, 2010
The main title of Robert J. Russell's Cosmology from Alpha to Omega: The Creative Mutual Interaction of Theology and Science catches the substance of the essays; the subtitle his methodological vision.
doaj   +2 more sources

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