Results 31 to 40 of about 129,344 (267)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
A Risk-Based Methodology and Tool Combining Threat Analysis and Power System Security Assessment
Energies, 2017 A thorough investigation of power system security requires the analysis of the vulnerabilities to natural and man-related threats which potentially trigger multiple contingencies.
Emanuele Ciapessoni +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
There and back again: consequences of biofilm specialization under selection for dispersal
Frontiers in Genetics, 2015 Experimental evolution paired with modern sequencing can be a powerful approach to identify the mechanisms by which bacteria adapt to discrete environmental conditions found in nature or during infections.
Devon eO'Rourke +3 more
doaj +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Annals of Clinical and Translational Neurology, EarlyView.Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source
Dini Araştırmalar, 2016 Kozmos olarak kabul edilen evrenin açıklanmasına dayanan kozmolojik delil, teistikdelillerin en eskisidir. Platon ve Aristoteles’in delillerinin çıkış noktası evrendekihareketin kökenini soruşturmaktır.
Metin Pay
doaj +1 more source
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García +3 more
wiley +1 more source
To take a liking to this faint contour (of experience) – two samples from Robert Creeley
Poznańskie Studia Polonistyczne. Seria Literacka, 2009 The present sketch discusses two poems written by R. Creeley, a poet initially associated with the Black Mountain College group, who later worked out his own idiosyncratic style, often referred to as minimalistic.
Kacper Bartczak
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England +9 more
wiley +1 more source
Advanced Biology, EarlyView.This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira +11 more
wiley +1 more source