Results 41 to 50 of about 108,030 (266)
Les raisonnements contrefactuels dans l’histoire
Argumentation et Analyse du Discours, 2020 This paper deals with the diverse types of counterfactual reasoning – particularly those one encounters in historiography and more generally in essays dealing with historical events.
Marc Angenot
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
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Neorealism, Contingency and the Linguistic Turn
Humanities, 2019 Since the publication of Roman Jakobson’s famous 1956 essay “Two Aspects of Language and Two Types of Aphasic Disturbances”, we have tended to read the relationship between metaphor and metonymy as a dialectical one.
Thomas Claviez
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
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A Risk-Based Methodology and Tool Combining Threat Analysis and Power System Security Assessment
Energies, 2017 A thorough investigation of power system security requires the analysis of the vulnerabilities to natural and man-related threats which potentially trigger multiple contingencies.
Emanuele Ciapessoni +7 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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There and back again: consequences of biofilm specialization under selection for dispersal
Frontiers in Genetics, 2015 Experimental evolution paired with modern sequencing can be a powerful approach to identify the mechanisms by which bacteria adapt to discrete environmental conditions found in nature or during infections.
Devon eO'Rourke +3 more
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FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
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Dini Araştırmalar, 2016 Kozmos olarak kabul edilen evrenin açıklanmasına dayanan kozmolojik delil, teistikdelillerin en eskisidir. Platon ve Aristoteles’in delillerinin çıkış noktası evrendekihareketin kökenini soruşturmaktır.
Metin Pay
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Arthritis Care &Research, EarlyView.Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
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