Results 41 to 50 of about 521,359 (300)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Resilient Distribution System Reconfiguration Based on Genetic Algorithms Considering Load Margin and Contingencies

Energies
This paper addresses the challenge of restoring electrical service in distribution systems (DS) under contingency scenarios using a genetic algorithm (GA) implemented in MATLAB.
Jorge Muñoz, Luis Tipán, Cristian Cuji, Manuel Jaramillo   +3 more
doaj   +1 more source

SAYING AND DOING: A CONTINGENCY‐SPACE ANALYSIS [PDF]

Journal of Applied Behavior Analysis, 1987
Correspondences between verbal responding (saying) and nonverbal responding (doing) may be organized in terms of the classes of verbal/nonverbal relations into which particular instances of verbal/nonverbal response sequences can enter. Contingency spaces, which display relations among events in terms of the probability of one event given or not given ...
B A, Matthews, E, Shimoff, A C, Catania
openaire   +2 more sources

Markov chain Monte Carlo tests for designed experiments

, 2006
We consider conditional exact tests of factor effects in designed experiments for discrete response variables. Similarly to the analysis of contingency tables, a Markov chain Monte Carlo method can be used for performing exact tests, when large-sample ...
Agresti, Akimichi Takemura, Aoki, Aoki, Aoki, Condra, Diaconis, Dinwoodie, Dobra, Freeman, Haberman, Hamada, Hastings, Hibi, McCullagh, Mehta, Pistone, Pistone, Robbiano, Satoshi Aoki, Takemura, Takemura   +21 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Secure Operation of Integrated Natural Gas and Electricity Transmission Networks

Energies, 2020
The interaction between natural gas and electricity networks is becoming more significant due to the projected large penetration of renewables into the energy system to meet the emission targets.
Ali Mohammad Rostami, Hossein Ameli, Mohammad Taghi Ameli, Goran Strbac   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Evaluating machine learning models for the fast identification of contingency cases

Applied AI Letters, 2020
Fast approximations of power flow results are beneficial in power system planning and live operation. In planning, millions of power flow calculations are necessary if multiple years, different control strategies, or contingency policies are to be ...
Florian Schäfer, Jan‐Hendrik Menke, Martin Braun   +2 more
doaj   +1 more source

Graphical Log-linear Models: Fundamental Concepts and Applications [PDF]

, 2016
We present a comprehensive study of graphical log-linear models for contingency tables. High dimensional contingency tables arise in many areas such as computational biology, collection of survey and census data and others. Analysis of contingency tables
Gauraha, Niharika
core   +3 more sources