Results 161 to 170 of about 430,365 (280)

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu   +12 more
wiley   +1 more source

Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using PET and Plasma Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown   +14 more
wiley   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

open access: yesAnnals of Neurology, EarlyView.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell   +13 more
wiley   +1 more source

Contingency awareness shapes neural responses in fear conditioning. [PDF]

open access: yesNeurosci Conscious
Pavlov YG   +3 more
europepmc   +1 more source

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates

open access: yesAngewandte Chemie International Edition, EarlyView.
This work presents the first enzymatic polymerization of defined metal‐chelator‐modified nucleotides that leverage polymerase fidelity for uniform (radio)metal loading with successful incorporation of five different metals: Ga, In, Tb, Lu, and Y.
Antonio A. W. L. Wong   +2 more
wiley   +1 more source

Diagnostic and prognostic utility of neutrophil CD64 and monocyte HLA-DR in adult sepsis patients. [PDF]

open access: yesBMC Res Notes
Arora K   +5 more
europepmc   +1 more source

The Effect of Demineralization on Coal Functional Group Pyrolysis: Rank‐Dependent Dual Mechanisms of Structural Reorganization and Mineral Catalysis

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Coal pyrolysis, as a key thermochemical conversion process, is significantly influenced by inherent minerals, yet their role across different coal ranks remains inadequately understood. This study investigates the effect of acid‐washing (demineralization) on the thermal decomposition of six functional groups (aliphatic C–H, aromatic C–H/C=C, C=
Zhiyuan Niu   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy