Results 31 to 40 of about 428,052 (282)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Nearest Neighbor Methods for Testing Reflexivity and Species-Correspondence [PDF]

open access: yes, 2014
Nearest neighbor (NN) methods are employed for drawing inferences about spatial patterns of points from two or more classes. We consider Pielou's test of niche specificity which is defined using a contingency table based on the NN relationships between ...
Ceyhan, Elvan
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Examining the Discrimination of Binary Scored Test Items with ROC Analysis

open access: yesInternational Journal of Assessment Tools in Education, 2021
In this study, it was claimed that ROC analysis, which is used to determine to what extent medical diagnosis tests can be differentiated between patients and non-patients, can also be used to examine the discrimination of binary scored items in cognitive
Sait Çüm
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Alternative Approaches to the Analysis of Multidimensional Contingency Tables [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2011
The practical analyses of interactions between categorical variables in various areas (such as public opinion research or marketing research) are often only applications of chi-square tests in two-way contingency tables. However, in many situations it is
Iva Pecáková
doaj  

Subsymmetry and asymmetry models for multiway square contingency tables with ordered categories

open access: yesOpen Mathematics, 2016
This paper suggests several models that describe the symmetry and asymmetry structure of each subdimension for the multiway square contingency table with ordered categories.
Aktaş Serpil
doaj   +1 more source

Distribuição espacial da precipitação sobre o Rio Grande do Norte: estimativas via satélites e medidas por pluviômetros Rainfall spatial distribution over the Rio Grande do Norte brazilian State: satellites estimates and rain gauges measurements

open access: yesRevista Brasileira de Meteorologia, 2012
O objetivo deste estudo foi avaliar as estimativas de precipitação mensal fornecidas por duas fontes (algoritmo 3B43_V6 e Universidade de Delaware) para o Estado do Rio Grande do Norte, no período de 1998 a 2008.
Cláudio Moisés Santos e Silva   +2 more
doaj   +1 more source

The stochastic encounter-mating model

open access: yes, 2016
We propose a new model of permanent monogamous pair formation in zoological populations with multiple types of females and males. According to this model, animals randomly encounter members of the opposite sex at their so-called firing times to form ...
Gün, Onur, Yilmaz, Atilla
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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