Results 151 to 160 of about 44,268 (251)

Multimodal brain network topology and enhanced computer-aided diagnosis in Parkinson's Disease: a systematic review and meta-analysis. [PDF]

NPJ Digit Med
Zuo C, Liu W, Lan H, Chen L, Li N, Yan Y, Li L, Luo C, Kemp GJ, Lui S, Suo X, Gong Q.   +11 more
europepmc   +1 more source

Conversational Topic Shifts and Topic Maintenance in Autistic and Neurotypical Children

Autism Research, EarlyView.
ABSTRACT Topic maintenance and topic shifts are crucial components of conversation; however, existing research lacks a clear quantitative operationalization of these topic management skills. Previous studies suggest that autistic children are less likely than their neurotypical peers to maintain and elaborate on the interlocutor's prior topic, and that
Zuriñe Ábalos, Mikhail Kissine, Agustín Vicente, Elena Castroviejo   +3 more
wiley   +1 more source

Receptive–Expressive Language Phenotypes in Infants and Toddlers With Autism Features

Autism Research, EarlyView.
ABSTRACT Children diagnosed with autism often present with an atypical discrepancy between their receptive and expressive language levels, or an atypical receptive–expressive language phenotype. Children with an atypical receptive–expressive phenotype present with a relative receptive language advantage (expressive level < receptive level) or a ...
Torrey Cohenour, Amanda Gulsrud, Connie Kasari   +2 more
wiley   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Recalibrating evidence: a cautionary note on the use of post hoc thresholds in IPD meta-analyses. [PDF]

Eur Thyroid J
Arredondo Montero J.
europepmc   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Microplastics in Sediments Originating from Abandoned, Lost or Discarded Fishing Gear (ALDFG) in Coastal Areas of the Valencian Community. [PDF]

Biology (Basel)
Romeo L, Perdichizzi A, Profeta A, Vitale D, Franch VC, Casu M, Spinelli A.   +6 more
europepmc   +1 more source

Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Depressive Symptoms in Patients With SARS-CoV-2 and Acute Coronary Syndrome. [PDF]

Cureus
Gonjilashvili A, Tatishvili S.
europepmc   +1 more source