Results 91 to 100 of about 6,899,630 (383)
NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer
Advanced Science, EarlyView.Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen +8 more
wiley +1 more source
Jurnal Manajemen dan Wirausaha, 2008 This research therefore uses configuration and contingency theory to establish if there is a relationship between export performance and the level of ‘fit’ between a firm’s strategic orientation and its context.
Muafi Muafi
doaj
RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
Advanced Science, EarlyView.Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang +12 more
wiley +1 more source
From Causes for Database Queries to Repairs and Model-Based Diagnosis and Back [PDF]
, 2014 In this work we establish and investigate connections between causes for query answers in databases, database repairs wrt. denial constraints, and consistency-based diagnosis.
Bertossi, Leopoldo, Salimi, Babak
core +3 more sources
Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems
Advanced Science, EarlyView.Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li +6 more
wiley +1 more source
Advanced Science, EarlyView.High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani +10 more
wiley +1 more source
ORGANIZATIONAL CHANGE- DIFFERENT APPROACHES [PDF]
As organizations decide to expand on other markets, managers are facing with new problems and realities. If thirty years ago, companies afford to ignore the international business environment, today they need to think globally.
Georgiana Surdu
core
AN ASSESSMENT OF THE CONTINGENCY THEORY OF MIS [PDF]
, 1987 The purpose of this paper is to define and critique the use of contingency theory in the field of Management Information Systems (MIS). The existence of such a theory is demonstrated through a detailed review of the MIS literature.
Olson, Margrethe H., Weill, Peter
core
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Organizational Mission and Revenue Diversification among Non-profit Sports Clubs
International Journal of Financial Studies, 2013 The beneficial effects of diversified income portfolios are well documented in previous research on non-profit organizations. This study examines how different types of organizational missions affect the level of revenue diversification of organizations ...
Christoph Breuer +2 more
doaj +1 more source