Results 71 to 80 of about 10,023 (313)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu   +18 more
wiley   +1 more source

FAKTOR-FAKTOR YANG BERPENGARUH TERHADAP WILLINGNESS TO PAY UNTUK PERBAIKAN KUALITAS AIR SUNGAI CODE DI KOTA YOGYAKARTA

open access: yesJurnal Ekonomi & Studi Pembangunan, 2007
This paper studies socio-economic factors influencing perceptions of the people on water quality improvement of the “Code” River in Yogyakarta. The factors considered in this study such as gender, number of children in family, income, duration of stay ...
endah saptutyningsih
doaj  

Contingent Valuation Method and the beta model: an accounting economic vision for environmental damage in Atlântico Sul Shipyard

open access: yesRevista Contabilidade & Finanças, 2018
The objective of this paper is to apply the beta model as an alternative to the Valuation Method in order to estimate the environmental asset Willingness to Pay (WTP) so that the Tribunal de Contas do Estado de Pernambuco (TCE/PE) can supervise the ...
Silvana Karina de Melo Travassos   +2 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Controlling starting-point bias in double-bounded contingent valuation surveys [PDF]

open access: yes
In this paper, we study starting point bias in double-bounded contingent valuation surveys. This phenomenon arise in applications that use multiple valuation questions.
Emmanuel Flachaire, Guillaume Hollard
core  

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

What Do Respondents Bring to Contingent Valuation? A Comparison of Monetary and Labor Payment Vehicles [PDF]

open access: yes
With contingent valuation, both the goods being valued and the payment vehicles used to value them are mostly hypothetical. However, although numerous studies have examined the impact of experience with the good on willingness to pay, less attention has ...
Eggert, Hakan   +3 more
core  

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

HOW USEFUL IS CONTINGENT VALUATION OF THE ENVIRONMENT TO WATER SERVICES? EVIDENCE FROM SOUTH EAST, NIGERIA [PDF]

open access: yes
Contingent Valuation Methods (CVM) Willingness To Pay (WTP) Tobit (censored) model Quasi ...
Adenuga Adeniyi   +2 more
core  

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

open access: yesAdvanced Science, EarlyView.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang   +7 more
wiley   +1 more source

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