Results 81 to 90 of about 308 (220)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Translating and Adapting Research Bioethical Principles to the African Socio-Cultural Contexts: An Integrative Review. [PDF]

Afr J Bioeth
Njie-Carr VPS, Senghore T, Sey-Sawo J, Usuf E, Yeboah J, Ceesay S, Dampha I, Omotosho TF, Jitteh F, Marega J, Janha RE, Sarpong LO, Awua AK, Jegede AS, Oduwole EO.   +14 more
europepmc   +1 more source

Continuous chromatin state feature annotation of the human epigenome. [PDF]

Bioinformatics, 2022
Daneshpajouh H, Chen B, Shokraneh N, Masoumi S, Wiese KC, Libbrecht MW.   +5 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Beyond the Lab: Cognitive Neuroscience in Real-World Contexts. [PDF]

Wiley Interdiscip Rev Cogn Sci
Kaufhold SP, Borzello M, Rossano F, Kirsh D.   +3 more
europepmc   +1 more source

Cognition and Daily Functioning: Results from the Hispanic Community Health Study/Study of Latinos (SOL) and Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA). [PDF]

J Alzheimers Dis, 2020
Stickel AM, Tarraf W, Wu B, Marquine MJ, Vásquez PM, Daviglus M, Estrella ML, Perreira KM, Gallo LC, Lipton RB, Isasi CR, Kaplan R, Zeng D, Schneiderman N, González HM.   +14 more
europepmc   +1 more source

Semantic projection recovers rich human knowledge of multiple object features from word embeddings. [PDF]

Nat Hum Behav, 2022
Grand G, Blank IA, Pereira F, Fedorenko E.   +3 more
europepmc   +1 more source

Convexification of Locally Connected Generalized Continua

Hiroshima Mathematical Journal, 1955
Tominaga, Akira, Tanaka, Tadashi
openaire   +3 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source