Results 91 to 100 of about 1,269,624 (326)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Un peu de « répit » le temps d’un récit : nécessités du répit dans la construction d’un cycle romanesque au XIIIe siècle

open access: yesCahiers de Narratologie
L’article s’intéresse au paradoxe à la source de la construction narrative du cycle des Sept Sages de Rome, en vue de témoigner de la complexité du mode d’écriture cyclique au cœur de nombreuses productions littéraires médiévales. Sur le modèle des Mille
Prunelle Deleville
doaj   +1 more source

The Functional Equation and Beyond Endoscopy

open access: yes, 2012
In his paper "Beyond Endoscopy," Langlands tries to understand functoriality via poles of L-functions. The following paper further investigates the analytic continuation of a L-function associated to a $GL_2$ automorphic form through the trace formula ...
Herman, P. Edward
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Dynamical zeta functions for Axiom A flows

open access: yes, 2018
We show that the Ruelle zeta function of any smooth Axiom A flow with orientable stable/unstable spaces has a meromorphic continuation to the entire complex plane.
Dyatlov, Semyon, Guillarmou, Colin
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Las insistencias de lo real. Escenas de reescritura en narrativas de no ficción argentinas

open access: yesCuadernos LIRICO
This article explores the question of rewriting as it is presented in nonfiction narratives, based on a series of Argentine texts that include Rodolfo Walsh's Operación masacre (1957), Tomás Eloy Martínez's La pasión según Trelew (1973) and María Moreno ...
Victoria García
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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