Results 121 to 130 of about 1,269,624 (326)

Continuation of Direct Products of Distributions

open access: yes, 2000
If, in some problems, one has to deal with the ``product'' of distributions $\rm f_i$ (also called generalized functions) $\rm\bar T = \Pi^m_{i=1} f_i$, this product has a priori no definite meaning as a functional $(\rm \bar T, \phi) $ for $\rm\phi \in ...
Petermann, A.
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Intention toward the continuation of female genital mutilation in Bale Zone, Ethiopia

open access: yesInternational Journal of Women's Health, 2015
Daniel Bogale,1 Desalegn Markos,2 Muhammedawel Kaso1 1Department of Public Health, 2Department of Nursing, College of Medicine and Health Sciences, Madawalabu University, Bale Goba, Ethiopia Background: Female genital mutilation (FGM) is a harmful ...
Bogale D, Markos D, Kaso M
doaj  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Study on the stable and high-precision downward extension method of airborne gravity anomaly data

open access: yes地球与行星物理论评
The essence of the downward continuation of airborne gravity anomalies is to solve the first kind of Fredholm integral equation, which is an ill-posed problem. Stable and high-precision downward continuation methods have always been a research hotspot in
Baogui Ke   +4 more
doaj   +1 more source

Some continuation properties via minimax arguments

open access: yes, 2011
This note is devotes to some remarks regarding the use of variational methods, of minimax type, to establish continuity type ...
Jeanjean, Louis
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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