Results 51 to 60 of about 15,074 (239)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Convergence properties of the classical and generalized Rogers-Ramanujan continued fraction [PDF]
Research in Number Theory, 2015 This paper was written during the Cologne Young Researchers in Number Theory Program 2015; 15 ...
Ciolan, Emil-Alexandru +1 more
openaire +3 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Continued Fractions and Generalizations with Many Limits: A Survey
, 2019 There are infinite processes (matrix products, continued fractions, $(r,s)$-matrix continued fractions, recurrence sequences) which, under certain circumstances, do not converge but instead diverge in a very predictable way. We give a survey of results in this area, focusing on recent results of the authors.
Bowman, Douglas, Laughlin, James Mc
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Generalized Bilateral Eighth Order Mock Theta Functions and Continued Fractions
Revista Colombiana de Matemáticas, 2019 We give a two independent variable generalization of bilateral eighth order mock theta functions and expressed them as infinite product. On specializing parameters, we have given a continued fraction representation for the generalized function, which I think is a new representation.
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On general two-point continued fraction expansions and Padé tables
Journal of Approximation Theory, 1991 A general M-fraction introduced by McCabe and Murphy is related to two power series expansions of a function: about the points \(z=0\) and \(z=\infty\). The table (M-table) of convergents of the M-fraction presents a square block structure, like the similar structure of a Padé table.
Achuthan, P, Ponnuswamy, S
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source