Results 51 to 60 of about 668 (225)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Continued fractions and the Thomson problem. [PDF]
Sci Rep, 2023 Moscato P, Haque MN, Moscato A.
europepmc +1 more source
General correspondence for continued fractions
Journal of Computational and Applied Mathematics, 1987 The author extends the definition of general convergence for continued fractions with complex elements \(K(a_ n/b_ n)\)- which uses the notion of chordal metric d on the Riemann sphere - to the case where \(a_ n\), \(b_ n\) belong to an arbitrary field \({\mathbb{F}}\) and d is replaced by any bounded metric, say d, on \({\hat {\mathbb{F}}}={\mathbb{F}}
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Generalized Brouncker’s continued fractions and their logarithmic derivatives [PDF]
The Ramanujan Journal, 2013 In this paper, we study the continued fraction y(s,r) which satisfies the equation y(s,r)y(s+2r,r)=(s+1)(s+2r-1) for r > 1/2. This continued fraction is a generalization of the Brouncker's continued fraction b(s). We extend the formulas for the first and the second logarithmic derivatives of b(s) to the case of y(s,r).
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The quantum chaos conjecture and generalized continued fractions [PDF]
Sbornik: Mathematics, 2003 Summary: The proof of the quantum chaos conjecture is given for a class of systems including as a special case the model of a rotating particle under the action of periodic impulse perturbations. (The distribution of the distances between adjacent energy levels is close to the Poisson distribution and differs from it by terms of the third order of ...
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source