Results 51 to 60 of about 795 (255)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Approximation Properties of Two-Dimensional Continued Fractions
, 2003 За допомогою формули різниці для наближень двовимірного неперервного дробу, методу фундаментальних нерівностей, теореми Стільтьєса - Віталі та узагальнення розділених та обернених різниць встановлено оцінки точності наближень двовимірних неперервних ...
Сусь, О.М. +2 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
First-order linear recurrence systems and matrix continued fractions [PDF]
, 1995 We introduce a matrix continued fraction associated with the first-order linear recurrence system Y_k = θ_k Y_{k-1}. A Pincherle type convergence theorem is proved.
Bultheel, Adhemar, Levrie, Paul
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Generalizations of Sturmian sequences associated with $N$-continued fraction algorithms [PDF]
, 2023 Given a positive integer $N$ and $x$ irrational between zero and one, an $N$-continued fraction expansion of $x$ is defined analogously to the classical continued fraction expansion, but with the numerators being all equal to $N$.
Thuswaldner, Jörg M. +2 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Chebyshev-like polynomials, conic distribution of roots, and continued fractions
, 2020 In the first part of this thesis, we show that a wide range of the properties of the roots of translated Chebyshev polynomials of the first kind (call these complex numbers Chebyshev points), are illuminated by the study of geometric properties of the ...
Oyengo, Michael Obiero
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source