Results 151 to 160 of about 584,519 (316)

Leaders as Agents of Continuity: Self-Continuity and Resistance to Collective Change

open access: yes, 2008
You cannot step into the same self twice. As Heraclites observed, everything is in flux, and more recent insights suggest that this observation includes the self-concept (Markus & Wurf, 1987; Turner, Hogg, Oakes, Reicher, & Wetherell, 1987).
VAN KNIPPENBERG B.   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Business Continuity Management and Strategic Planning: the Case of Jordan

open access: yes
Business Continuity Management (BCM) is a process that focuses on counteracting organizational risk, disasters and crises. Placing Business Continuity Management in the context of Strategic Planning (SP) will help organizations to cope with a wide range ...
Sawalha, Ihab Hanna
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

The challenges of evaluating midwifery continuity of care

open access: yes, 2008
In this chaprer) we describe some of the challenges associated with evaluating midwifery continuity of care. The notion of 'midwifery care as a complex intervention' is explored as this informs (he way it is evaluated.
Foureur, M, Sandall, J
core  

'I giovanni delle colonne.' Tradition and continuity ante litteram.

open access: yesCuadernos de Proyectos Arquitectónicos, 2015
In the mid 50’s background of the Politecnico di Milano, a group of students started to make use of a range of very personal stylistical references in the academic ex tempore, related to a specifi c historical and traditional baggage, giving thus birth ...
Francesca Fiorelli
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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