Results 181 to 190 of about 750,466 (305)

ON CONTINUOUS MARTINGALES [PDF]

open access: yesProceedings of the National Academy of Sciences, 1965
Dubins, L. E., Schwarz, G.
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

CONTINUITY OF MULTIFUNCTIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1965
openaire   +2 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Nursing-Led Support Across the Standard Care-Clinical Trial-Standard Care Pathway in Inflammatory Bowel Disease: A Review With Realist-Informed Interpretation. [PDF]

open access: yesJGH Open
Napolitano D   +10 more
europepmc   +1 more source

Continuous Particles [PDF]

open access: yesProceedings of the National Academy of Sciences, 1947
openaire   +2 more sources

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