Results 171 to 180 of about 198,076 (205)

Melanin as a Redox Hub: Linking Energy Flow to Genome Stability and Immune Control. [PDF]

Antioxid Redox Signal
Srivastava J, Premi S.
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Genetic affinities between the ancient Greek colony of Amvrakia and its metropolis. [PDF]

Genome Biol
Psonis N, Tabakaki E, Vassou D, Papadantonakis S, Souleles A, Nafplioti A, Kousis Tsampazis G, Papadopoulou A, Xanthopoulos K, Panailidis P, Georgiadou A, Papakosta D, Koursioti S, Evangelinou M, Papadopoulou V, Evaggeloglou P, Korka E, Christidis I, Ioannou M, Kontogianni T, Arkoumanis A, Stamatakis A, Poulakakis N, Papageorgopoulou C, Pavlidis P.   +24 more
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Caring, pragmatic and discriminatory: how private paediatric outpatient providers normalise unequal care for Roma-ethnographic findings from affluent Slovakia. [PDF]

Int J Equity Health
Cichová K, Belak A.
europepmc   +1 more source

Integrating Robotics in Hospital and Home Education: A Systematic Review of Innovative Teaching Practices. [PDF]

Contin Educ
Pelizzari F, Rocco S, Ferrari S.
europepmc   +1 more source

Root causes and fields of action to address unplanned hospitalisation in long-term care: a multiple case study with root-cause analysis. [PDF]

BMC Nurs
Pohontsch NJ, Huckle TA, Jarchow AM, Balzer K, Silies KT.   +4 more
europepmc   +1 more source