Results 121 to 130 of about 203,487 (306)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The continuity care of quality of long term services for the elderly users

open access: yes, 2009
[[abstract]]Long-term care services in Taiwan provided by three systems have their own service targets and regulations which are not easy to provide integral and continuity care for aged people.
hung i chi
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Feasibility of tele-rehabilitation in survivors of COVID-19 pneumonia

open access: yesPulmonology, 2022
M. Paneroni   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

UPDATE: Consistency of Home Care Personnel Under Managed Competition: A Case Study from Ontario (Shortened Version Presented at the Knowledge to Wisdom Conference) [PDF]

open access: yes
Measuring Consistency of Personnel in Home care: Current Challenges and Findings Consistency of personnel is important to ensuring continuity of care for home care clients.
Brian Hutchison   +3 more
core  

Models of maternity care: Evidence for midwifery continuity of care

open access: yes, 2016
© 2016 AMPCo Pty Ltd. Produced with Elsevier B.V. All rights reserved. • There has been substantial reform in the past decade in the provision of maternal and child health services, and specifically regarding models of maternity care.
Homer, CSE
core   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Continuity of care: vital, but how do we measure and promote it?

open access: yes, 2018
Background Continuity of care is a fundamental element of traditional general practice linked, via an expanding evidence base, with important patient and system outcomes.
Jackson, Claire, Ball, Lauren
core   +1 more source

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