Results 171 to 180 of about 896,711 (397)

Electronic Consultations Between Primary and Specialty Care Clinicians: Early Insights [PDF]

open access: yes, 2011
Outlines how e-consultation enables clinicians and specialists to communicate more easily and reduce the need for in-person referrals; experiences for patients, clinicians, and health systems; benefits such as continuity of care; and barriers to ...
Ed Wagner, Jim Tufano, Kathryn Horner
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Rethinking continuity in primary care for people with mesothelioma [PDF]

open access: bronze, 2023
Emilie Couchman   +3 more
openalex   +1 more source

Continuity of care: a multidisciplinary review

open access: yesBritish medical journal, 2003
J. Haggerty   +5 more
semanticscholar   +1 more source

Understanding the Experience of Weight Gain and Body Image During Adolescent Pregnancy [PDF]

open access: yes, 2012
This qualitative descriptive study explores the experience of adolescent pregnancy and the influence of body image and other factors on weight gain. It identified three main themes through content analysis: Continuity of Care, Adolescent Investment in a ...
Hinkley, Jessica L., Newcombe, Liana J.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Gaps in continuity of care at the interface between primary care and specialized care: general practitioners’ experiences and expectations

open access: yesInternational Journal of General Medicine, 2011
Ryan Tandjung, Thomas Rosemann, Nina BadertscherInstitute of General Practice and Health Services Research, University of Zurich, SwitzerlandIntroduction: Discontinuity of care at the interface between inpatient and outpatient management can lead to ...
Tandjung R, Rosemann T, Badertscher N
doaj  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The triple challenges associated with age-related comorbidities in Down syndrome [PDF]

open access: yes, 2014
Background Major increases in the survival of people with Down syndrome during the last two generations have resulted in extended periods of adulthood requiring specialist care, which in turn necessitates greater understanding of the nature, timing and ...
Bittles, A.H., Dye, D.E., Glasson, E.J.
core   +1 more source

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