Results 171 to 180 of about 5,228,638 (296)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest. [PDF]

Resuscitation
Liu R, Nadkarni VM, Berg RA, Morgan RW, Topjian AA, Kirschen MP.   +5 more
europepmc   +1 more source

CONTINUITY OF MULTIFUNCTIONS [PDF]

Proceedings of the National Academy of Sciences, 1965
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Barbed Sutures Are Associated With a Lower Incidence of Incisional Hernia Compared With Continuous Non-Barbed Monofilament Sutures After Minimally Invasive Gastroenterological Surgery. [PDF]

Ann Gastroenterol Surg
Honma S, Takashima T, Ushikubo T, Ishikawa K, Kumode T, Suzuki T, Murakami T, Hosokawa S, Nakajima S.   +8 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Continuous-Flow Synthesis of Antiepileptic Drugs: Process Intensification, Sustainability Metrics, and Scalable Manufacturing. [PDF]

ACS Omega
Upadhyay A, Raj Pandey A, Mishra A, Tewari S.   +3 more
europepmc   +1 more source

Continuous Particles [PDF]

Proceedings of the National Academy of Sciences, 1947
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease. [PDF]

J Parkinsons Dis
De Bartolo MI, Marchet F, Pietracupa S, Cutrona C, Aiello F, Costanzo M, Leodori G, Vivacqua G, Conte A, Fabbrini G, Berardelli A, Modugno N, Belvisi D.   +12 more
europepmc   +1 more source