Results 221 to 230 of about 572,064 (244)
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Comprehensive review in continuous direct compression process
Journal of Pharmaceutical InvestigationMi-Seon Na +4 more
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International Journal of Pharmaceutics
This feasibility study evaluates a cleaning process designed to avoid the use of detergents and reduce operator exposure to the active pharmaceutical ingredient (API). The continuous manufacturing equipment was cleaned using excipients to displace ibuprofen residues from the system. The cleaning process was performed using 3.0 kg of Prosolv® and 3.0 kg
Dhavalkumar S. Patel +2 more
openaire +3 more sources
This feasibility study evaluates a cleaning process designed to avoid the use of detergents and reduce operator exposure to the active pharmaceutical ingredient (API). The continuous manufacturing equipment was cleaned using excipients to displace ibuprofen residues from the system. The cleaning process was performed using 3.0 kg of Prosolv® and 3.0 kg
Dhavalkumar S. Patel +2 more
openaire +3 more sources
Direct delta mush skinning compression with continuous examples
ACM Transactions on Graphics, 2021Direct Delta Mush (DDM) is a high-quality, direct skinning method with a low setup cost. However, its storage and run-time computing cost are relatively high for two reasons: its skinning weights are 4 X 4 matrices instead of scalars like other direct skinning methods, and its computation requires one 3 X 3 Singular Value Decomposition per vertex.
Binh Huy Le +2 more
openaire +1 more source
International journal of pharmaceutics, 2021
Near Infrared (NIR) spectroscopy is commonly utilized for continuous manufacturing as Process Analytical Technology (PAT) tool. This paper focus on a continuous direct compression manufacturing process, in which an NIR PAT probe is integrated into the ...
G. Cogoni +4 more
semanticscholar +1 more source
Near Infrared (NIR) spectroscopy is commonly utilized for continuous manufacturing as Process Analytical Technology (PAT) tool. This paper focus on a continuous direct compression manufacturing process, in which an NIR PAT probe is integrated into the ...
G. Cogoni +4 more
semanticscholar +1 more source
Flowsheet modeling of a continuous direct compression process
2018Seongkyu Yoon +3 more
openaire +2 more sources
International journal of pharmaceutics, 2022
Continuous manufacturing (CM) offers advantages in quality and space-time yield compared to common batch manufacturing. However, higher yield losses due to the start-up procedure make a broad application uneconomical.
M. Peterwitz +3 more
semanticscholar +1 more source
Continuous manufacturing (CM) offers advantages in quality and space-time yield compared to common batch manufacturing. However, higher yield losses due to the start-up procedure make a broad application uneconomical.
M. Peterwitz +3 more
semanticscholar +1 more source
International journal of pharmaceutics, 2022
Continuous manufacturing of pharmaceuticals promises many advantages regarding economics and quality. However, tracing deviating material in such processes is much more challenging than in batch processes due to axial back-mixing.
Peterwitz Moritz +3 more
semanticscholar +1 more source
Continuous manufacturing of pharmaceuticals promises many advantages regarding economics and quality. However, tracing deviating material in such processes is much more challenging than in batch processes due to axial back-mixing.
Peterwitz Moritz +3 more
semanticscholar +1 more source
A Demonstration of Mixing Robustness in a Direct Compression Continuous Manufacturing Process
Journal of Pharmaceutical Sciences, 2017The purpose of this work was to assess the impact of continuous mixing on tablet critical quality attributes (CQAs) manufactured using a continuous, direct compression process. A 9-run design of experiments (DoE) that bracketed the range of commercially relevant mixer speeds, mixer orientations, and mass flow rates was executed using a formulation ...
Wyatt J, Roth +3 more
openaire +2 more sources
Journal of the Society of Powder Technology, Japan, 2021
Takahiro Hagihara +2 more
openaire +1 more source
Takahiro Hagihara +2 more
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