Results 61 to 70 of about 486,113 (257)

Review and Prospect of Integration Compatibility in Digital Vehicles: Multi-Dimensional Challenges and Industry Practice

Machines
Integration compatibility has emerged as a prominent challenge in the development of digital vehicles. This paper provides a comprehensive review of previous research on automotive integration compatibility, categorizing the relevant challenges into ...
Wang Zhang, Meng Shi, Xinglong Liu, Linjie Ren   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

UMLRev: A Context-Aware Feature-Oriented Approach to Support Continuous Reverse Engineering of UML Models

IEEE Access
Maintaining up-to-date design models is a persistent challenge in modern software development, especially within continuous integration (CI) environments.
Kleinner Farias, Lucas Schenatto, Cristiano Farias, Willian Bolzan, Robson Keemps, Carlos Carbonera   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A Policy-Driven Branching and Environment Isolation Strategy for Enterprise DevSecOps: An Empirical Industrial Case Study

IEEE Access
As enterprise software systems transition toward rapid delivery cycles, traditional branching models often introduce significant merge choreography and environment-specific bottlenecks that hinder developer velocity.
Gaurav Bhatnagar
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Test Pyramid 2.0: AI-assisted testing across the pyramid

Frontiers in Artificial Intelligence
Ensuring robust test coverage, high code quality, and a strong security posture are persistent challenges in modern industrial software development, especially as systems grow in complexity and release cycles accelerate with recent Artificial ...
Priyank Desai, Snahil Singh, Shubham Amilkanthwar   +2 more
doaj   +1 more source

The Continuous Primitive Integral in the Plane

Real Analysis Exchange, 2020
An integral is defined on the plane that includes the Henstock--Kurzweil and Lebesgue integrals (with respect to Lebesgue measure). A space of primitives is taken as the set of continuous real-valued functions $F(x,y)$ defined on the extended real plane $[-\infty,\infty]^2$ that vanish when $x$ or $y$ is $-\infty$.
openaire   +4 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Integrated Visual Software Analytics on the GitHub Platform

Computers
Readily available software analysis and analytics tools are often operated within external services, where the measured software analysis data are kept internally and no external access to the data is available. We propose an approach to integrate visual
Willy Scheibel, Jasper Blum, Franziska Lauterbach, Daniel Atzberger, Jürgen Döllner   +4 more
doaj   +1 more source