Active and Continuous Exploration with Deep Neural Networks and Expected Model Output Changes [PDF]
, 2016 Christoph Käding +3 more
openalex +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A Continuous Root Water Uptake Isotope Mixing Model
Water Resources ResearchThe depth‐wise distribution of root water uptake is typically inferred through linear mixing models that utilize knowledge of stable water isotopes in soil and plants.
Han Fu +3 more
doaj +1 more source
Continuous Wavelet Transform and Hidden Markov Model Based Target Detection [PDF]
, 2014 Standard tracking filters perform target detection process by comparing the sensor output signal with a predefined threshold. However, selecting the detection threshold is of great importance and a wrongly selected threshold causes two major problems ...
Efe, M., Tuğaç, S.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Bisimulation, Logic and Reachability Analysis for Markovian Systems [PDF]
, 2008 In the recent years, there have been a large amount of investigations on safety verification of uncertain continuous systems. In engineering and applied mathematics, this verification is called stochastic reachability analysis, while in computer science ...
Bujorianu, L.M., Bujorianu, M.C.
core +2 more sources
A Study on the Factors Affecting the Continuous Use Intention of Chinese Health Apps: Focusing on the Extended Technology Acceptance Model [PDF]
, 2023 Yabo Dong, Mina Lee
openalex +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Continuous-spontaneous-localization scalar-field relativistic collapse model
Physical Review Research, 2019 The continuous-spontaneous-localization dynamical collapse structure, adapted to the relativistically invariant model where the collapse-generating operator is a one-dimensional scalar field ϕ[over ̂](x,t) (mass m) is discussed.
Daniel Bedingham, Philip Pearle
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source