Results 81 to 90 of about 5,918,114 (348)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Continuous Model of Income Insurance [PDF]
We develop a simple yet realistic model of income insurance, where the individual’s ability and willingness to work is treated as a continuous variable.
Lindbeck, Assar, Persson, Mats
core +4 more sources
Continuous publishing model of Malaysian Family Physician [PDF]
Malaysian Family Physician, 2023 Ping Yein Lee
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2000 We investigate four-dimensional N=1 Type IIB orientifolds with continuous Wilson lines, and their T-dual realizations as orientifolds with moving branes.
Aldazabal +23 more
core +2 more sources
Delay Cournot Duopoly Game with Gradient Adjustment: Berezowski Transition from a Discrete Model to a Continuous Model [PDF]
, 2020 Akio Matsumoto +2 more
openalex +1 more source
Continual Unsupervised Generative Modeling
IEEE Transactions on Pattern Analysis and Machine IntelligenceVariational Autoencoders (VAEs), can achieve remarkable results in single tasks learning of data representations, image generation, and image-to-image translation among others. However, VAEs suffer from loss of information when aiming to continuously learn a sequence of different data domains.
Fei Ye, Adrian G. Bors
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Continuous Model Averaging for Benchmark Dose Analysis: Averaging Over Distributional Forms. [PDF]
Environmetrics, 2022 Wheeler MW +4 more
europepmc +1 more source
Broad Histogram Method for Continuous Systems: the XY-Model
, 1998 We propose a way of implementing the Broad Histogram Monte Carlo method to systems with continuous degrees of freedom, and we apply these ideas to investigate the three-dimensional XY-model with periodic boundary conditions.
de Oliveira P. M. C. +2 more
core +1 more source