Results 91 to 100 of about 8,956,014 (290)

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Domiciliary nasal respiratory support : first experiences in Malta [PDF]

, 1997
Nasal respiratory support is a non-invasive alternative to conventional assisted ventilation with endotracheal intubation, or the more cumbersome negative pressure ventilators.
Camilleri, Robert, Galea Debono, Anthony, Montefort, Stephen   +2 more
core  

Mechanism and disaster control new technology of strong ground pressure manifestation in ultra‐large mining face

Deep Underground Science and Engineering, EarlyView.
In response to the problem of strong mining pressure manifestation along the goaf roadway in a thick coal seam mining area, this study uses a new type of combined blasting roof cutting technology to effectively control the manifestation and deformation of mining pressure along the goaf roadway.
Xiaoding Xu, Manchao He, Jun Yang, Yubing Gao, Qiang Fu, Qing Ma, Yajun Wang   +6 more
wiley   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Multivariate linear regression to predict association of non‐invasive arterial stiffness with cardiovascular events

ESC Heart Failure, Volume 12, Issue 2, Page 1141-1150, April 2025.
Abstract Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the relationship between arterial stiffness and future CVD.
Susan Darroudi, Mostafa Eslamiyeh, Amin Mansoori, Eisa Nazar, Maryam Alinezhad‐Namaghi, Reza Rezvani, Majid Ghayour‐Mobarhan, Habibollah Esmaily, Mohsen Moohebati, Gordon A. Ferns, Mark Ghamsary   +10 more
wiley   +1 more source

Comparison of seven infant continuous positive airway pressure systems using simulated neonatal breathing

, 2012
Objective: Continuous positive airway pressure is an established treatment for respiratory distress in neonates. Continuous positive airway pressure has been applied to infants using an array of devices.
Kjell Nilsson, Henrik Zetterström, Zetterstrom, H, Baldvin Jonsson, Drevhammar, Thomas, Thomas Drevhammar, Nilsson, Kjell, Drevhammar, T,, Zetterström, Henrik,, Jonsson, B,, Jonsson, Baldvin, Nilsson, K   +11 more
core   +1 more source

Superimposed high-frequency jet ventilation combined with continuous positive airway pressure/assisted spontaneous breathing improves oxygenation in patients with H1N1-associated ARDS [PDF]

, 2012
Background: Numerous cases of swine-origin 2009 H1N1 influenza A virus (H1N1)-associated acute respiratory distress syndrome (ARDS) bridged by extracorporeal membrane oxygenation (ECMO) therapy have been reported; however, complication rates are high. We
Wolf, Timo, Koch, Alexander, Rosenberger, Peter, Peter Rosenberger, Tobias M Bingold, Bertram Scheller, Scheller, Bertram, Jens Meier, Thomas Iber, Alexander Koch, Timo Wolf, Zacharowski, Kai, Kai Zacharowski, Iber, Thomas, Bingold, Tobias Michael, Meier, Jens   +15 more
core   +1 more source

Epilepsy educational curriculum for nurses: A report from the Nursing Section of the International League Against Epilepsy

Epileptic Disorders, EarlyView.
Abstract A comprehensive, competency‐based epilepsy curriculum is needed to strengthen nurses' capacity to care for people with epilepsy worldwide. Such a curriculum should be adaptable across nursing roles, practice settings, and geographic regions.
Patricia O. Shafer, Sandra Dewar, Ariane Bernier, Ludivine Rohrer, Nancy Santilli, Carmela Redhead, Tammy Gravel, Gagandeep Singh, Jane R. von Gaudecker   +8 more
wiley   +1 more source

Microbiome and Mycobiome Analyses of Continuous Positive Airway Pressure Devices [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. Microorganisms are likely present in continuous positive airway pressure (CPAP) devices in daily use. Given the potential risk of infection among CPAP users, we aimed to compare the microbiomes of CPAP devices with those of nasal mucosa ...
Hyun Jin Min, Bo-Yun Choi, Woo Jun Sul, Hyung-Ju Cho   +3 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source