Results 91 to 100 of about 189,861 (389)

Devoted or negotiated routes of adherence: Narratives of patients with obstructive sleep apnoea using a continuous positive airway pressure device

Nursing Open, 2019
Aims To explore the narratives of patients about receiving a diagnosis of obstructive sleep apnoea and using a continuous positive airway pressure device. Design A qualitative design with a narrative approach.
Margareta Møkleby, Anne Marit Mengshoel
doaj   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

The Effect of Continuous Positive Airway Pressure on Middle Ear Pressure

Southeastern European Medical Journal
Aim of the study: The study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure. Methods: Forty-two patients with obstructive sleep apnea (OSA) were assigned to the study group. The patients underwent standard
Mirjana Grebenar Čerkez, Željko Zubčić, Stjepan Jurić, Jelena Šarić Jurić, Jelena Kovačević, Darko Dukić, Darija Birtić   +6 more
doaj   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

P54 Positive role of continuous positive airway pressure for intensive care unit patients with severe hypoxaemic respiratory failure due to COVID-19 pneumonia: a single centre experience [PDF]

, 2021
DR Wozniak, A Rubino, ALW Tan, NL Jones, Stephen Webb, Alain Vuylsteke, Earl Palas, TG Quinnell, IE Smith, MG Davies   +9 more
openalex   +1 more source

Cardiovascular outcomes of continuous positive airway pressure therapy for obstructive sleep apnea.

Journal of Thoracic Disease, 2018
Obstructive sleep apnea is a common disorder with increased risk for cardiovascular morbidity and mortality. The first choice of treatment of obstructive sleep apnea is continuous positive airway pressure, which reduces excessive daytime sleepiness and ...
Y. Peker, B. Balcan
semanticscholar   +1 more source

Medical versus science students: Knowledge, perceptions and learning of core pharmacology concepts

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmacology is a core discipline underpinning both medical and biomedical science education, essential for understanding drug action, safety and therapeutic efficacy. This study compared pharmacology knowledge, perceptions and learning experiences between second‐year medical and science students to evaluate how effectively each curriculum ...
Zina Alfahl, Rachel Lynch, Cara O'Dwyer, John P. Kelly   +3 more
wiley   +1 more source

Continuous positive airway pressure increases CSF flow and glymphatic transport

JCI Insight, 2023
Respiration can positively influence cerebrospinal fluid (CSF) flow in the brain, yet its effects on central nervous system (CNS) fluid homeostasis, including waste clearance function via glymphatic and meningeal lymphatic systems, remain unclear.
Burhan Ozturk, Sunil Koundal, Ehab Al Bizri, Xinan Chen, Zachary Gursky, Feng Dai, Andrew Lim, Paul Heerdt, Jonathan Kipnis, Allen Tannenbaum, Hedok Lee, Helene Benveniste   +11 more
doaj   +1 more source

Long-term efficacy of an education programme in improving adherence with continuous positive airway pressure treatment for obstructive sleep apnoea [PDF]

, 2017
This randomised controlled trial demonstrated that a motivational enhancement programme composed of a single interview and a follow-up phone call at the initiation of continuous positive airway pressure treatment can improve treatment adherence in ...
Fong, D, Ip, M, Lai, A, Lam, J
core  

Management of Mechanical Ventilation in Decompensated Heart Failure. [PDF]

, 2016
Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular preload and afterload, decrease extra-vascular lung water, and decrease the work of breathing ...
Adams, Jason Y, Bradley, Laura A, Dempsey, Timothy M, Kuhn, Brooks T, Puro, Alana C   +4 more
core   +4 more sources