Results 121 to 130 of about 8,956,014 (290)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Noninvasive Positive Pressure Ventilation or Conventional Mechanical Ventilation for Neonatal Continuous Positive Airway Pressure Failure

International Journal of Preventive Medicine, 2014
Background: The aim of this study was to assess the success rate of nasal intermittent positive pressure ventilation (NIPPV) for treatment of continuous positive airway pressure (CPAP) failure and prevention of conventional ventilation (CV) in preterm ...
Zohreh Badiee, Babak Nekooie, Majid Mohammadizadeh   +2 more
doaj  

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Cardiorespiratory interaction with continuous positive airway pressure

, 2018
The treatment of choice for obstructive sleep apnoea (OSA) is continuous positive airway pressure therapy (CPAP). Since its introduction in clinical practice, CPAP has been used in various clinical conditions with variable and heterogeneous outcomes.
Sara Bonafini, Bonafini, Sara, Fava, Cristiano, Steier, Joerg, Martino F. Pengo, Cristiano Fava, Joerg Steier, Pengo, Martino F   +7 more
core   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Effects of different continuous positive airway pressure devices and periodic hyperinflations on respiratory function.

, 2001
OBJECTIVE: To compare the effect on respiratory function of different continuous positive airway pressure systems and periodic hyperinflations in patients with respiratory failure.
PELOSI, PAOLO PASQUALINO, CHIUMELLO D, PANIGADA M, CALVI E, BOTTINO N, CADRINGHER P, GATTINONI L., TACCONE P   +7 more
core   +1 more source

Enhanced alcohol metabolism and sleep quality with continuous positive airway pressure following alcohol consumption

Scientific Reports
We aimed to examine the effect of continuous positive airway pressure on sleep quality and alcohol metabolism after alcohol consumption. Men (n = 53) aged ≥ 19 years with sleep disorders who regularly consumed an average of ≥ 1.0 g of alcohol/kg of ...
Hyun Jun Kim, Do-Yang Park, Wee Gyo Lee, Kang Il Lee, Jin Ji Jung, Han Sang Lee, Sang In Hwang, Ji Hyun Park, Bumhee Park   +8 more
doaj   +1 more source

Sex differences of continuous positive airway pressure treatment on flow-mediated dilation in patients with obstructive sleep apnea syndrome

, 2015
Anastasios Kallianos,1 Athanasios Panoutsopoulos,1 Christoforos Mermigkis,2 Konstantinos Kostopoulos,1 Chrysanthi Papamichail,1 Ioannis Kokkonouzis,3 Christoforos Kostopoulos,1 Ioannis Nikolopoulos,4 Antonis Papaiwannou,5 Sofia Lampaki,5 John Organtzis,5
Organtzis J, Nikolopoulos I, Mermigkis C, Kokkonouzis I, Lampaki S, Papaiwannou A, Kallianos A, Trakada G, Papamichail C, Kostopoulos K, Pitsiou G, Kostopoulos C, Panoutsopoulos A, Zarogoulidis P   +13 more
core  

Diaphragm Ultrasonography Reveals Progressive Changes in Diaphragmatic Function, Morphology, and Muscle Trophism During Invasive Mechanical Ventilation in Children

Journal of Clinical Ultrasound, EarlyView.
Diaphragm ultrasonography detected progressive structural and functional deterioration in mechanically ventilated children. Prolonged invasive mechanical ventilation and neuromuscular blocking agent use were associated with ventilator‐induced diaphragmatic dysfunction, highlighting ultrasound as a valuable bedside tool to support individualized ...
Juliana Bezerra dos Santos, Emmerson Carlos Franco de Farias, Mary Lucy Ferraz Maia Fiuza de Mello, Rodrigo Santiago Barbosa Rocha   +3 more
wiley   +1 more source

Integrating Dental Sleep Medicine Into Dental Education: A Comprehensive Framework for Curriculum and Clinical Practice

Journal of Dental Education, EarlyView.
ABSTRACT Dental sleep medicine (DSM) is increasingly relevant to dental practice, yet its integration into dental education remains variable. Recent Commission on Dental Accreditation (CODA) standards, adopted in 2026 and effective July 1, 2028, include risk assessment for sleep apnea within predoctoral dental education, further highlighting the need ...
Mark Vaughan, Audrey Yoon, Joorok Park, Heesoo Oh   +3 more
wiley   +1 more source