Results 31 to 40 of about 4,751,282 (207)

Cascaded processing enables continuous upstream processing with E. coli BL21(DE3)

Scientific Reports, 2021
In many industrial sectors continuous processing is already the golden standard to maximize productivity. However, when working with living cells, subpopulation formation causes instabilities in long-term cultivations. In cascaded continuous cultivation,
Stefan Kittler, Christoph Slouka, Andreas Pell, Roman Lamplot, Mihail Besleaga, Sarah Ablasser, Christoph Herwig, Oliver Spadiut, Julian Kopp   +8 more
doaj   +1 more source

The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry

Beilstein Journal of Organic Chemistry, 2015
The implementation of continuous flow processing as a key enabling technology has transformed the way we conduct chemistry and has expanded our synthetic capabilities.
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source

Processing continuous and discrete quantities.

, 2014
Processing continuous and discrete quantities.
Bruno Marques Panccioni (605465), Andreia Miranda Domingues (605467), Marcus Vasconcelos de Castro (605463), Silvia Cristina Martini Rodrigues (605466), Márcia Aparecida Silva Bissaco (605464)   +4 more
core   +1 more source

A Slug Flow Platform with Multiple Process Analytics Facilitates Flexible Reaction Optimization

Advanced Science
Flow processing offers many opportunities to optimize reactions in a rapid and automated manner, yet often requires relatively large quantities of input materials.
Florian Wagner, Peter Sagmeister, Clemens E. Jusner, Thomas G. Tampone, Vidhyadhar Manee, Frederic G. Buono, Jason D. Williams, C. Oliver Kappe   +7 more
doaj   +1 more source

Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells

iScience, 2020
Summary: Human embryonic kidney cells HEK293 can be used for the production of therapeutic glycoproteins requiring human post-translational modifications.
Caijuan Zhan, Gholamreza Bidkhori, Hubert Schwarz, Magdalena Malm, Aman Mebrahtu, Ray Field, Christopher Sellick, Diane Hatton, Paul Varley, Adil Mardinoglu, Johan Rockberg, Veronique Chotteau   +11 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

A Comprehensive Review on Bigels as a Potential Replacement to Solid Fat in Food Applications

Journal of Food Quality
Bigels, composed of hydrogels and oleogels, are emerging as innovative materials with significant potential in the food industry. This review explores the application of bigels in various food contexts, including conventional and novel meats, plant-based
Wasiya Farzana, Sneha Mahesh, Sachin Sharma, Irshaan Syed, Gholamreza Abdi, Rituja Upadhyay   +5 more
doaj   +1 more source

Structure of 2-chloro-N-(p-tolyl)propanamide

Acta Crystallographica Section E: Crystallographic Communications, 2018
Two independent samples of the title compound, alternatively 2-chloro-N-(4-methylphenyl)propanamide, C10H12ClNO, 1, were studied using Cu Kα, 1a, and Mo Kα, 1b, radiation as part of a continuous crystallization study.
Roderick C. Jones, Brendan Twamley
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Continuous crystallisation [PDF]

, 2017
Although crystallisation in pharmaceutical manufacturing is traditionally carried out as a batch operation, with the drive towards implementing continuous manufacturing of pharmaceuticals there is increased interest in developing and applying approaches ...
Alastair Florence, Cameron Brown, Florence, Alastair, Thomas McGlone, McGlone, Thomas, Brown, Cameron   +5 more
core   +2 more sources