Results 41 to 50 of about 3,461,601 (198)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Volume 4, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1006/thumbnail ...
Spectrum Contributors,
core +1 more source
Spectrum Sensor Employing Continuous Pilot Tones in Cognitive Radio Systems
Despite the promising role of orthogonal frequency-division multiplexing (OFDM) in communication systems, the optimal and practical spectrum sensing of OFDM signals for cognitive radio systems over multipath fading channels remains an important and ...
Wen-Long Chin
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
We describe and implement an efficient, open-source, multi-platform computer program ReSpect to infer the continuous and discrete relaxation spectra from dynamic moduli measurements obtained by small-angle oscillatory shear experiments.
Takeh Arsia, Shanbhag Sachin
doaj +1 more source
A Nonlinear Static Procedure for the Seismic Design of Symmetrical Irregular Bridges
Displacement-based seismic design methods support the performance-based seismic design philosophy known to be the most advanced seismic design theory. This paper explores one common type of irregular-continuous bridges and studies the prediction of their
Shanshan Li +4 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
The article presents the experimental studies results of continuous spectrum pulsed UV light mycobactericidal activity against the laboratory strain of Mycobacterium terrae and clinical strains of Mycobacterium tuberculosis with multiple and extensive ...
V. I. Litvinov +5 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

