Results 61 to 70 of about 201,875,683 (208)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Other title: Report and Recommendations
, 2017 "Presented to Wes Cole, Chair, GBHSPC."; "December 7, 2017."; Includes bibliographical and internet references."The Children's Continuum of Care Task Force, CCC, was established at the request of Secretary Tim Keck of the Kansas Department for Aging and ...
Children's Continuum of Care Task Force (Kan.).
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Software Abstractions for Simulation and Control of a Continuum Robot [PDF]
, 2012 Nordmann A, Rolf M, Wrede S. Software Abstractions for Simulation and Control of a Continuum Robot.
Wrede, Sebastian ; https://orcid.org/ +5 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 2017 Updated.; "January 5, 2017.""The ACC Task Force endorses the 2015 Report. These recommendations do not replace the recommendations of the 2015 Report and interested parties should read the full 2015 Report to provide context to this document. The members
Kansas. Department for Aging and Disability Services. Adult Continuum of Care Committee.
core
, 1986 The Continuum of Care program in the South Carolina Office of Executive Policy and Programs published an annual report with information on the activities and accomplishments of the agency as it served children with severe emotional ...
South Carolina Office of Executive Policy and Programs, Continuum of Care
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source