Results 111 to 120 of about 59,579 (312)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
An Integrated Procedure for Shape Optimization Applied to Fluid Flow
Trends in Computational and Applied Mathematics, 2006 This work proposes an integrated numerical procedure for the shape optimization of fluid flow problems. The procedure is named integrated since it combines various distinct modules for the solution to the problem, such as: geometric modeling, mesh ...
L.M. Steffens, M.K. Alves
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Vortical control of forced two-dimensional turbulence [PDF]
, 2013 A new numerical technique for the simulation of forced two-dimensional turbulence (Dritschel and Fontane, 2010) is used to examine the validity of Kraichnan-Batchelor scaling laws at higher Reynolds number than previously accessible with classical pseudo-
Fontane, Jérôme +8 more
core +1 more source
Retention of Local Information in Generation of Subjective Contours
Vision Research, 1997 Temporal integration characteristics of subjective contour perception was investigated, using the sequential presentation of two pairs of disks with a sector removed. In the first experiment, by matching the contrast of a "real" stimulus, the perceived contrast of the subjective contours was measured as a function of the stimulus onset asynchrony (SOA)
TAKEMOTO, ATSUSHI, EJIMA, YOSHIMICHI
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Topographically forced long waves on a sheared coastal current. Part 2. Finite amplitude waves
, 1997 This paper analyses the finite-amplitude flow of a constant-vorticity current past coastal topography in the long-wave limit. A forced finite-amplitude long-wave equation is derived to describe the evolution of the vorticity interface.
Johnson, ER, Clarke, SR
core
Static Hand Gesture Recognition Based on Convolutional Neural Networks
Journal of Electrical and Computer Engineering, 2019 This paper proposes a gesture recognition method using convolutional neural networks. The procedure involves the application of morphological filters, contour generation, polygonal approximation, and segmentation during preprocessing, in which they ...
Raimundo F. Pinto +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source