Results 191 to 200 of about 59,579 (312)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A UAV RGB dataset and method for instance tree crown segmentation for biodiversity monitoring. [PDF]

open access: yesSci Rep
Do MVH   +10 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Lens-based approach for bespoke contour beam generation with single feed source for satellite applications

open access: yes
The paper presents a first-of-its-kind concept for bespoke contour beam generation using a homogeneous dielectric lens with a single feed antenna. Contour beams are used to cover specific regions of the planet and are traditionally created using a ...
Aakash Bansal (16512855)   +2 more
core  

Uncertainty quantification of U-Net based segmentation tool using conformal prediction. [PDF]

open access: yesJ Appl Clin Med Phys
Borden BJ   +4 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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