Results 281 to 290 of about 4,108,186 (369)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Optimization of PETG 3D printing parameters for the design and development of biocompatible bone implants. [PDF]

Front Bioeng Biotechnol
Sultan MM, Aized T, Farooq M, Anwar S, Ahmad N, Tauseef A, Riaz F.   +6 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Temporal Contour Integration Deficits in Children With Amblyopia. [PDF]

Invest Ophthalmol Vis Sci
Chen YR, Jiang SQ, Liu XY, Zhang JY.
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Counting touching wheat grains in images based on elliptical approximation. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Avzalov DR, Komyshev EG, Afonnikov DA.
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Combined contour error control method for five-axis machine tools based on digital twin. [PDF]

Sci Rep
Wang L, Yang R, Lv S, Yang Z, Xin S, Liu Y, Liu Q.   +6 more
europepmc   +1 more source

Spheroid Cell Aggregation Enhanced by Enzyme‐Free Ultrasound‐Detached Cells

Advanced Biology, EarlyView.
This study demonstrates that ultrasound‐based, enzyme‐free cell detachment accelerates spheroid formation by preserving surface proteins, reducing variability, and enhancing cell aggregation. Comparable engraftment and improved spatial organization in co‐cultured spheroids are observed.
Julien van Delft, Chikahiro Imashiro, Yuta Kurashina, Makoto Hirano, Jun Homma, Shinsuke Mochizuki, Hideharu Shimozawa, Kenjiro Takemura   +7 more
wiley   +1 more source

Stahl's ear correction: A review of surgical approaches. [PDF]

JPRAS Open
Nassar A, Naba J, Eid D, Zeid SA, Demian J.   +4 more
europepmc   +1 more source