Results 131 to 140 of about 2,660 (259)
Advanced Turboprop Project [PDF]
At the direction of Congress, a task force headed by NASA was organized in 1975 to identify potential fuel saving concepts for aviation. The result was the Aircraft Energy Efficiency (ACEE) Program implemented in 1976.
Hager, Roy D., Vrabel, Deborah
core +1 more source
In order to improve the stability margin of the fan, the FBCDZ-No20 contra-rotating fan is selected as the research object, and the influence of the coupling effect of the axial position and the depth of the circumferential groove on the stability margin of the fan was explored.
Chen, Qingguang +3 more
openaire +1 more source
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Rotor systems research aircraft predesign study. Volume 4: Preliminary draft detail specification [PDF]
The RSRA requirements are presented in a detail specification format. Coverage of the requirements includes the following headings: (1) aircraft characteristics, (2) general features of design and construction, (3) aerodynamics, (4) structural design ...
Linden, A. W., Miller, A. N.
core +1 more source
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Effect of forward motion on engine noise [PDF]
Methods used to determine a procedure for correcting static engine data for the effects of forward motion are described. Data were analyzed from airplane flyover and static-engine tests with a JT8D-109 low-bypass-ratio turbofan engine installed on a DC-9-
Blankenship, G. L. +3 more
core +1 more source
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Advanced Science, EarlyView.This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu +9 more
wiley +1 more source