Results 31 to 40 of about 7,116 (267)

Numerical study on aerodynamic noise performances of axial spacing in a contra-rotating axial fan [PDF]

open access: yes, 2016
In order to study the effect of axial spacing on behaviors of aerodynamic performance and aerodynamic noises in a contra-rotating fan, the steady/unsteady Reynolds-averaged Navier-Stokes equations are solved by the numerical method in conjunction with a ...
Hengxuan Luan   +4 more
core   +2 more sources

Axial Spacing Effects on Rotor-Rotor Interaction Noise and Vibration in a Contra-Rotating Fan

open access: yesInternational Journal of Aerospace Engineering, 2019
Because of the potential technical advantages, the contra-rotation technology has become a renewed interest in aviation and other applications. Contra-rotation increases efficiency in comparison with the single-rotor design, but this advantage is not ...
Hengxuan Luan   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Trailing edge noise theory for rotating blades in uniform flow [PDF]

open access: yes, 2013
This paper presents a new formulation for trailing edge noise radiation from rotating blades based on an analytical solution of the convective wave equation. It accounts for distributed loading and the effect of mean flow and spanwise wavenumber.
Agarwal, Anurag   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Experimental comparison between a counter-rotating axial-flow fan and a conventional rotor-stator stage [PDF]

open access: yes, 2013
Based on the requirement of energy consumption level and weight and dimension restriction, compact axial machines are highly demanded in many industrial fields.
BAKIR, Farid   +2 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Scimitar Precooled Mach 5 Engine [PDF]

open access: yes, 2007
Accepted ...
Bond, A   +3 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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