Results 151 to 160 of about 408,639 (386)
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin+11 more
wiley +1 more source
Chilot Abiyu Demeke,1,* Asmamaw Emagn Kasahun,1,* Wudneh Simegn Belay,1 Abay Nega Chekol,2 Rahel Alemu Getaneh,2 Dawit Kumilachew Yimenu1 1Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Medicine and Health Sciences ...
Demeke CA+5 more
doaj
The effect of oral contraceptives on cortisol metabolism [PDF]
C. W. BURKE
openalex +1 more source
From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen+7 more
wiley +1 more source
Background: Antara injectable contraceptive is a safe, low-cost, reversible, and highly effective contraceptive method. The objectives of the study were to estimate the period prevalence of injectable contraceptive use and its determinants among women of
Preeti Solanki+2 more
doaj +1 more source
Contraceptive use and intent in Guatemala [PDF]
Guatemala is characterized by low contraceptive use rates and one of the highest fertility rates in the Western Hemisphere. These rates are particularly extreme for the poorest segment of the population and for the indigenous population.
Kathryn Grace
core
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer+8 more
wiley +1 more source
Co‐administration with MHC class I‐ and II‐restricted neoantigens encoding mRNA‐based personalized cancer vaccines in a mouse CRC model can induce antigen‐specific immune responses and anti‐cancer effects. Notably, vaccination at an early stage of cancer development can have potent anti‐cancer effects. Furthermore, combining mRNA with immune checkpoint
Seongje Cho+26 more
wiley +1 more source