Results 161 to 170 of about 408,639 (386)

Post-abortion contraceptive uptake, choices, and factors associated with it among women seeking abortion services in Africa: a systematic review and meta-analysis

open access: yesFrontiers in Global Women's Health
BackgroundIn Africa, over one-third of women experience multiple abortions, often due to inadequate access to effective modern contraceptives. This highlights a critical gap in understanding the patterns and predictors of post-abortion contraceptive (PAC)
Gizachew Worku Dagnew   +1 more
doaj   +1 more source

The Unfinished Agenda: Meeting the Need for Family Planning in Less Developed Countries [PDF]

open access: yes, 2004
Outlines the positive gains made by family planning programs over the past fifty years, and details the need for an increase in the use of modern contraception in developing ...
Dara Carr, Marya Khan
core  

Developing a Personalized Cancer Nanovaccine Using Coxsackievirus‐Reprogrammed Cancer Cell Membranes for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni   +6 more
wiley   +1 more source

Are Women In Lomé Getting Their Desired Methods Of Contraception? Understanding Provider Bias From Restrictions To Choice. [PDF]

open access: yes, 2019
Background: Despite improvements in contraception availability, women face persistent barriers that compromise reproductive autonomy and informed choice.
Koffi, Tekou   +4 more
core  

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun   +15 more
wiley   +1 more source

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

open access: yesAdvanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu   +12 more
wiley   +1 more source

Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. [PDF]

open access: yes, 2020
The contraceptive effectiveness of intrauterine devices (IUDs) has been attributed in part to a foreign body reaction in the endometrium. We performed this study to better understand mechanisms of action of contraceptives of by studying their effects on ...
Averbach, Sarah   +6 more
core  

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

open access: yesAdvanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen   +12 more
wiley   +1 more source

Male Involvement in Family Planning Utilization and Associated Factors in Womberma District, Northern Ethiopia: Community-Based Cross-Sectional Study

open access: yesOpen Access Journal of Contraception, 2020
Getinet Wondim,1 Genet Degu,2 Yohannes Teka,2 Gedefaw Diress3 1Key Population and Partner Notification Service, CDC, Woldia, Ethiopia; 2Department of Midwifery, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia ...
Wondim G, Degu G, Teka Y, Diress G
doaj  

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