Results 211 to 220 of about 22,954 (265)
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American Journal of Obstetrics and Gynecology, 2011
Currently available contraceptive methods have not eliminated the burden of unintended pregnancy. Future progress will require technological advancements, leading to the development of novel and highly effective birth control strategies that will be acceptable to the general population.
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Currently available contraceptive methods have not eliminated the burden of unintended pregnancy. Future progress will require technological advancements, leading to the development of novel and highly effective birth control strategies that will be acceptable to the general population.
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Novel antiangiogenic agents for use in contraception
Contraception, 2005Angiogenesis and vascular development are fundamental to the development of a receptive endometrium that permits implantation. The underlying hypothesis of this project is that implantation in primates and in humans is dependent on vascular remodeling in the endometrium and that the identification of agents that can disrupt this process prior to embryo
Andrew M, Sharkey +4 more
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Effect of contraceptive agents on drug metabolism
European Journal of Pharmacology, 1969Abstract A series of steroids including progesterone, medroxyprogesterone, norethynodrel, estrone, mestranol and ethynylestradiol have been administered either acutely of chronically, alone or in combination, to rats to test for possible effects on drug metabolism.
A, Jori, A, Bianchetti, P E, Prestini
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Quinestrol: A Potential Contraceptive Agent
Fertility and Sterility, 1969To test the contraceptive effectiveness of the estrogen derivative Quinestrol 6 women 23-30 years old with confirmed fertility were administered 1 mg Quinestrol orally on Days 1 8 and 15 of the cycle for a total of 34 treated cycles. A single oral dose of 20 mg medroxyprogesterone acetate was administered on Day 22 to achieve proper cyclic withdrawal ...
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Psychoendocrine Study of Oral Contraceptive Agents
American Journal of Psychiatry, 1970After briefly reviewing the literature of the psychiatric effects of oral contraceptives experimental evidence for sex hormones influencing catecholamines and the role of catecholamines in affective illness the author reported on a 2 month single-blind study of 7 women who took combined or sequential pills.
F J, Kane +3 more
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Update on male hormonal contraceptive agents
Expert Opinion on Investigational Drugs, 2004There remains a need for new acceptable and effective male contraceptives to increase the choice for couples throughout the world. There have been no recent advances in available male contraceptive methods although a number of promising approaches have been identified, of which the hormonal approach is currently undergoing clinical investigation.
Melanie, Walton, Richard A, Anderson
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Ulipristal acetate as an emergency contraceptive agent
Expert Opinion on Pharmacotherapy, 2012Emergency contraceptive agents play a crucial role in preventing unplanned pregnancy. These agents and devices have been studied since the 1960s and have had varied results in terms of side effects and efficacy. A new oral tablet for emergency contraception (EC), ulipristal acetate (UPA) , is a selective progesterone receptor modulator and can be used ...
Alan M, Martinez, Michael A, Thomas
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Newer Agents for Hormonal Contraception in the Male
Trends in Endocrinology & Metabolism, 2000Efforts to create a hormonal contraceptive for men use testosterone to suppress the production of pituitary gonadotropins and, hence, spermatogenesis. However, conventional testosterone must be administered by frequent injection, and when given alone, is not 100% effective.
J K, Amory, W J, Bremner
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Oral contraceptive agents: current status
The American Journal of Surgery, 1988Oral contraceptives are the most widely prescribed and ingested drug in human history. The difficulty in establishing their clear-cut side effects is compounded by the rarity of these side effects and their occurrence with multiple other factors and cofactors that may be etiologically more important.
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Metallic copper as an intrauterine contraceptive agent
American Journal of Obstetrics and Gynecology, 1973Abstract Some of the biological aspects of copper relevant to reproductive processes are reviewed. Included are cyclic variations in the concentrations of copper in the endometrium, uterine fluid, cervical mucus, and serum as modified by the presence of intrauterine metallic copper and after its removal. Variations in the endometrial enzymes, namely,
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