Results 261 to 270 of about 57,170 (314)

Novel antiangiogenic agents for use in contraception

Contraception, 2005
Angiogenesis and vascular development are fundamental to the development of a receptive endometrium that permits implantation. The underlying hypothesis of this project is that implantation in primates and in humans is dependent on vascular remodeling in the endometrium and that the identification of agents that can disrupt this process prior to embryo
Andrew M, Sharkey, Rob, Catalano, Amanda, Evans, D Stephen, Charnock-Jones, Stephen K, Smith   +4 more
openaire   +2 more sources

Endogenous Antispermatogenic Agents: Prospects for Male Contraception

Annual Review of Pharmacology and Toxicology, 1978
A review of endogenous antispermatogenic agents as prospects for male contraception is reported. It is demonstrated that endogenous compounds exert regulatory influences at 4 major levels in the male: 1) between germ cells; 2) between Sertoli and germ cells; 3) between Leydig cells and seminiferous tubules; and 4) between the central nervous system
L L, Ewing, B, Robaire
openaire   +2 more sources

Hypertension, Oral Contraceptive Agents, and Conjugated Estrogens

Annals of Internal Medicine, 1971
Abstract Twenty-two patients developed hypertension on oral contraceptive pills. Mean blood pressure of the group before, during, and after the medication was stopped was 125/76, 183/110, and 130/8...
M G, Crane, J J, Harris, W, Winsor
openaire   +2 more sources

Investigation of Danazol as a contraceptive agent

Contraception, 1976
Abstract Danazol, the 2,3-isoxasol derivative of 17 α -ethinyl testosterone, was administered to 17 healthy volunteers during the first 7 days of the menstrual cycle, to see if an inadequate luteal phase would result. The follicular span was lengthened, and FSH levels either did not increase or were lowered during Danazol dosage in most women ...
A C, Wentz, G S, Jones, K C, Sapp
openaire   +2 more sources

Effect of contraceptive agents on drug metabolism

European Journal of Pharmacology, 1969
Abstract A series of steroids including progesterone, medroxyprogesterone, norethynodrel, estrone, mestranol and ethynylestradiol have been administered either acutely of chronically, alone or in combination, to rats to test for possible effects on drug metabolism.
A, Jori, A, Bianchetti, P E, Prestini
openaire   +2 more sources

Ulipristal acetate as an emergency contraceptive agent

Expert Opinion on Pharmacotherapy, 2012
Emergency contraceptive agents play a crucial role in preventing unplanned pregnancy. These agents and devices have been studied since the 1960s and have had varied results in terms of side effects and efficacy. A new oral tablet for emergency contraception (EC), ulipristal acetate (UPA) , is a selective progesterone receptor modulator and can be used ...
Alan M, Martinez, Michael A, Thomas
openaire   +2 more sources

Estrogen-Containing Oral Contraceptive Agents

JAMA, 1976
Since studies on the effects of oral contraceptives (OCs) on antithrombin 3 have been conflicting the thrombogenic effects of estrogen were studied in 57 OC users and 48 controls focusing on the level of activated factor X (Xa). The women were aged 18-45 (average age for both groups 24).
openaire   +1 more source

Metallic copper as an intrauterine contraceptive agent

American Journal of Obstetrics and Gynecology, 1973
Abstract Some of the biological aspects of copper relevant to reproductive processes are reviewed. Included are cyclic variations in the concentrations of copper in the endometrium, uterine fluid, cervical mucus, and serum as modified by the presence of intrauterine metallic copper and after its removal. Variations in the endometrial enzymes, namely,
openaire   +2 more sources

Hypertension Secondary to Contraceptive Agents

1982
Agents used to prevent conception are generally of five main types: 1) mechanical barriers, e.g. sheaths and cervical diaphragms. 2) intra-uterine devices; these may be inert plastic, or contain a metal such as copper, or be impregnated with a hormone such as progesterone. 3) spermicidal creams, jelly or paste. 4)
openaire   +1 more source

Effects of oral contraceptive agents on carbohydrate metabolism

Journal of Steroid Biochemistry, 1975
This is a survey of recent data regarding the influence of conventional contraceptive steroids on carbohydrate metabolism. Evidence indicates that a continuum of sensitivity to sex steroids exists and the deterioration of glucose tolerance appears to parallel the preexisting state of pancreatic beta cell function.
openaire   +2 more sources