Results 301 to 310 of about 58,056 (359)
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Update on male hormonal contraceptive agents
Expert Opinion on Investigational Drugs, 2004There remains a need for new acceptable and effective male contraceptives to increase the choice for couples throughout the world. There have been no recent advances in available male contraceptive methods although a number of promising approaches have been identified, of which the hormonal approach is currently undergoing clinical investigation.
Melanie, Walton, Richard A, Anderson
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Quinestrol: A Potential Contraceptive Agent
Fertility and Sterility, 1969To test the contraceptive effectiveness of the estrogen derivative Quinestrol 6 women 23-30 years old with confirmed fertility were administered 1 mg Quinestrol orally on Days 1 8 and 15 of the cycle for a total of 34 treated cycles. A single oral dose of 20 mg medroxyprogesterone acetate was administered on Day 22 to achieve proper cyclic withdrawal ...
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The Pharmacology of Contraceptive Agents
Annual Review of Pharmacology, 1974Some aspects of the pharmacology and physiology of contraceptive agents administered to women are reviewed. Hormonal events during the normal menstrual cycle are described. Contraceptive compounds in addition to modifying the hormonal control of ovarian function also may act on later stages of fertility (i.e.
W. D. Odell, M. E. Molitch
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American Journal of Obstetrics and Gynecology, 2011
Currently available contraceptive methods have not eliminated the burden of unintended pregnancy. Future progress will require technological advancements, leading to the development of novel and highly effective birth control strategies that will be acceptable to the general population.
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Currently available contraceptive methods have not eliminated the burden of unintended pregnancy. Future progress will require technological advancements, leading to the development of novel and highly effective birth control strategies that will be acceptable to the general population.
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Novel antiangiogenic agents for use in contraception
Contraception, 2005Angiogenesis and vascular development are fundamental to the development of a receptive endometrium that permits implantation. The underlying hypothesis of this project is that implantation in primates and in humans is dependent on vascular remodeling in the endometrium and that the identification of agents that can disrupt this process prior to embryo
Andrew M, Sharkey +4 more
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Endogenous Antispermatogenic Agents: Prospects for Male Contraception
Annual Review of Pharmacology and Toxicology, 1978A review of endogenous antispermatogenic agents as prospects for male contraception is reported. It is demonstrated that endogenous compounds exert regulatory influences at 4 major levels in the male: 1) between germ cells; 2) between Sertoli and germ cells; 3) between Leydig cells and seminiferous tubules; and 4) between the central nervous system
L L, Ewing, B, Robaire
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Hypertension, Oral Contraceptive Agents, and Conjugated Estrogens
Annals of Internal Medicine, 1971Abstract Twenty-two patients developed hypertension on oral contraceptive pills. Mean blood pressure of the group before, during, and after the medication was stopped was 125/76, 183/110, and 130/8...
M G, Crane, J J, Harris, W, Winsor
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Investigation of Danazol as a contraceptive agent
Contraception, 1976Abstract Danazol, the 2,3-isoxasol derivative of 17 α -ethinyl testosterone, was administered to 17 healthy volunteers during the first 7 days of the menstrual cycle, to see if an inadequate luteal phase would result. The follicular span was lengthened, and FSH levels either did not increase or were lowered during Danazol dosage in most women ...
A C, Wentz, G S, Jones, K C, Sapp
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Effect of contraceptive agents on drug metabolism
European Journal of Pharmacology, 1969Abstract A series of steroids including progesterone, medroxyprogesterone, norethynodrel, estrone, mestranol and ethynylestradiol have been administered either acutely of chronically, alone or in combination, to rats to test for possible effects on drug metabolism.
A, Jori, A, Bianchetti, P E, Prestini
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Ulipristal acetate as an emergency contraceptive agent
Expert Opinion on Pharmacotherapy, 2012Emergency contraceptive agents play a crucial role in preventing unplanned pregnancy. These agents and devices have been studied since the 1960s and have had varied results in terms of side effects and efficacy. A new oral tablet for emergency contraception (EC), ulipristal acetate (UPA) , is a selective progesterone receptor modulator and can be used ...
Alan M, Martinez, Michael A, Thomas
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